CXCL13 and CXCR3

Number of citations of the paper that reports this interaction (PubMedID 11554781)
19

Data Source:
HPRD (in vivo, in vitro)

		CXCL13	CXCR3
Description		C-X-C motif chemokine ligand 13	C-X-C motif chemokine receptor 3
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane
	Molecular Function	Chemokine Activity Heparin Binding Fibroblast Growth Factor Binding CXCR5 Chemokine Receptor Binding CCR10 Chemokine Receptor Binding CXCR Chemokine Receptor Binding Receptor Ligand Activity CXCR3 Chemokine Receptor Binding	Chemokine Receptor Activity Protein Binding C-C Chemokine Receptor Activity C-X-C Chemokine Receptor Activity Chemokine Binding C-C Chemokine Binding
	Biological Process	Germinal Center Formation Lymphocyte Chemotaxis Across High Endothelial Venule Chronic Inflammatory Response Regulation Of Humoral Immune Response Inflammatory Response Immune Response Cell Surface Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Cell-cell Signaling Positive Regulation Of T Cell Chemotaxis Neutrophil Chemotaxis Positive Regulation Of Integrin Activation Positive Regulation Of Cell-cell Adhesion Mediated By Integrin B Cell Chemotaxis Endothelial Cell Chemotaxis To Fibroblast Growth Factor Defense Response To Bacterium Regulation Of Angiogenesis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide Activation Of GTPase Activity Negative Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor	Angiogenesis Regulation Of Leukocyte Migration Apoptotic Process Chemotaxis Inflammatory Response Immune Response Cell Adhesion Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration T Cell Chemotaxis Calcium-mediated Signaling Regulation Of Cell Adhesion Cell Chemotaxis Chemokine-mediated Signaling Pathway
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS		Cardiac Troponin-T levels ( 23247143) Diffusing capacity of carbon monoxide ( 30694715) Rheumatoid arthritis ( 32723749) Tonsillectomy ( 27182965 28928442) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		11 interacting genes: ACKR4 CCL19 CCL21 CCL28 CCL4L1 CCR10 CXCR3 CXCR5 EEF1G FGF2 PF4V1	9 interacting genes: C2CD2L CLDN19 CXCL10 CXCL11 CXCL13 CXCL9 FATE1 PF4 TMEM14A
Entrez ID		10563	2833
HPRD ID		05513	02936
Ensembl ID		ENSG00000156234	ENSG00000186810
Uniprot IDs		O43927 Q53X90	P49682
PDB IDs		5CBA 5CBE 6VGJ 7JNY
Enriched GO Terms of Interacting Partners?
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