GOLGB1 and PFN2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid, affinity chromatography technology)
HPRD (two hybrid)

		GOLGB1	PFN2
Description		golgin B1	profilin 2
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Golgi Stack Cis-Golgi Network Cytosol Membrane Integral Component Of Membrane	Cytoplasm Cytoskeleton Extracellular Exosome
	Molecular Function	RNA Binding Protein Binding Sequence-specific DNA Binding	Actin Binding Actin Monomer Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding ATP Hydrolysis Activity
	Biological Process	Regulation Of Transcription, DNA-templated Golgi Organization Chondrocyte Proliferation Protein Localization To Pericentriolar Material	Negative Regulation Of Epithelial Cell Migration Actin Cytoskeleton Organization Regulation Of Actin Filament Polymerization Negative Regulation Of Actin Filament Polymerization Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Actin Filament Bundle Assembly Positive Regulation Of ATPase Activity Positive Regulation Of Peptidyl-serine Phosphorylation Protein Stabilization Positive Regulation Of Stress Fiber Assembly Negative Regulation Of Ruffle Assembly
Pathways		Golgi Associated Vesicle Biogenesis COPI-mediated anterograde transport Signaling by FLT3 fusion proteins Signaling by FLT3 fusion proteins	Signaling by ROBO receptors RHO GTPases Activate Formins RHO GTPases Activate Formins
Drugs			Triglyme Pentaglyme
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean reticulocyte volume ( 32888494)	Fish- and plant-related diet ( 32066663)
Interacting Genes		19 interacting genes: ACBD3 ADRB2 BRMS1 CAV2 CEP126 ECPAS INTS5 ITSN2 MAPK7 NDUFA1 NOD2 PFN2 POGK SKIL SLC2A3 SREBF2 UBE2I USO1 VTI1B	34 interacting genes: ACTB ACTG1 ANTKMT BIRC2 CCDC113 DDX11 DLST DNM1 EEF1A1 ERCC6 EVL FHOD1 FLT3LG FMNL1 GOLGB1 HTT IK IVNS1ABP MSANTD3 MYPOP NDUFB8 PLAUR PTPRS RAP1GAP RNF146 ROCK1 RPS10 SEPTIN5 SGTA SNTA1 SYN1 TERF1 VASP WDR33
Entrez ID		2804	5217
HPRD ID		03933	01451
Ensembl ID		ENSG00000173230	ENSG00000070087
Uniprot IDs		Q14789	P35080
PDB IDs			1D1J
Enriched GO Terms of Interacting Partners?
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