SGSM3 and FMO3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SGSM3	FMO3
Description		small G protein signaling modulator 3	flavin containing dimethylaniline monoxygenase 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Gap Junction	Endoplasmic Reticulum Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	GTPase Activator Activity Protein Binding Small GTPase Binding	Monooxygenase Activity N,N-dimethylaniline Monooxygenase Activity Protein Binding Trimethylamine Monooxygenase Activity Flavin Adenine Dinucleotide Binding NADP Binding
	Biological Process	Intracellular Protein Transport Cell Cycle Regulation Of Rab Protein Signal Transduction Rap Protein Signal Transduction Positive Regulation Of GTPase Activity Positive Regulation Of Protein Catabolic Process Plasma Membrane To Endosome Transport Activation Of GTPase Activity Regulation Of Cilium Assembly
Pathways			FMO oxidises nucleophiles Defective FMO3 causes TMAU
Drugs
Diseases
GWAS		Body mass index ( 26426971) Breast size ( 29855537) Chronotype ( 27494321) Height ( 19570815) Mammographic density (dense area) ( 25342443) Morning vs. evening chronotype ( 27494321) Refractive error ( 32231278) Regular attendance at a pub or social club ( 29970889)	Blood metabolite levels ( 24816252) Lentiform nucleus volume ( 22903471) Serum metabolite levels ( 33031748)
Interacting Genes		9 interacting genes: CHRM3 FMO3 GJA1 NF2 RAB39B RAB5A RAB5B RAB5C RPL35	5 interacting genes: CLEC10A CREB3 SACM1L SERPINC1 SGSM3
Entrez ID		27352	2328
HPRD ID		15285	00633
Ensembl ID		ENSG00000100359	ENSG00000007933
Uniprot IDs		B4DVE3 B9A6J5 Q96HU1	A0A024R8Z4 B7Z3M2 B7Z543 P31513 Q53FW5
PDB IDs
Enriched GO Terms of Interacting Partners?
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