FMO3 and SGSM3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FMO3	SGSM3
Description		flavin containing dimethylaniline monoxygenase 3	small G protein signaling modulator 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Cytosol Gap Junction
	Molecular Function	Monooxygenase Activity N,N-dimethylaniline Monooxygenase Activity Protein Binding Trimethylamine Monooxygenase Activity Flavin Adenine Dinucleotide Binding NADP Binding	GTPase Activator Activity Protein Binding Small GTPase Binding
	Biological Process		Intracellular Protein Transport Cell Cycle Regulation Of Rab Protein Signal Transduction Rap Protein Signal Transduction Positive Regulation Of GTPase Activity Positive Regulation Of Protein Catabolic Process Plasma Membrane To Endosome Transport Activation Of GTPase Activity Regulation Of Cilium Assembly
Pathways		FMO oxidises nucleophiles Defective FMO3 causes TMAU
Drugs
Diseases
GWAS		Blood metabolite levels ( 24816252) Lentiform nucleus volume ( 22903471) Serum metabolite levels ( 33031748)	Body mass index ( 26426971) Breast size ( 29855537) Chronotype ( 27494321) Height ( 19570815) Mammographic density (dense area) ( 25342443) Morning vs. evening chronotype ( 27494321) Refractive error ( 32231278) Regular attendance at a pub or social club ( 29970889)
Interacting Genes		5 interacting genes: CLEC10A CREB3 SACM1L SERPINC1 SGSM3	9 interacting genes: CHRM3 FMO3 GJA1 NF2 RAB39B RAB5A RAB5B RAB5C RPL35
Entrez ID		2328	27352
HPRD ID		00633	15285
Ensembl ID		ENSG00000007933	ENSG00000100359
Uniprot IDs		A0A024R8Z4 B7Z3M2 B7Z543 P31513 Q53FW5	B4DVE3 B9A6J5 Q96HU1
PDB IDs
Enriched GO Terms of Interacting Partners?
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