TOR1B and NFATC3

		TOR1B	NFATC3
Description		torsin family 1 member B	nuclear factor of activated T cells 3
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Lumen Nuclear Membrane Extracellular Exosome	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Cytosol
	Molecular Function	Protein Binding ATP Binding ATP Hydrolysis Activity Kinesin Binding Identical Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Response To Unfolded Protein Endoplasmic Reticulum Organization Protein Localization To Nucleus Chaperone Cofactor-dependent Protein Refolding Nuclear Membrane Organization	Cytokine Production Regulation Of Transcription By RNA Polymerase II Inflammatory Response Calcineurin-NFAT Signaling Cascade Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Pri-miRNA Transcription By RNA Polymerase II Negative Regulation Of Vascular Associated Smooth Muscle Cell Differentiation
Pathways		Cargo recognition for clathrin-mediated endocytosis	Calcineurin activates NFAT Calcineurin activates NFAT FCERI mediated Ca+2 mobilization CLEC7A (Dectin-1) induces NFAT activation
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Liver enzyme levels (alanine transaminase) ( 33972514) Percent liver fat ( 34128465)	Chronotype ( 30696823) Estimated glomerular filtration rate ( 31015462) Fasting glucose ( 33402679) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656) Serum alkaline phosphatase levels ( 33547301) Urate levels ( 31578528)
Interacting Genes		4 interacting genes: KCNJ15 MRPS2 NFATC3 TOR1A	13 interacting genes: CALB2 CDK6 CELSR2 CSNK1A1 FOS KCNJ3 MAPK8 MAPK9 MYOCD SEC24A SNX20 TOR1B TTF1
Entrez ID		27348	4775
HPRD ID		16270	04077
Ensembl ID		ENSG00000136816	ENSG00000072736
Uniprot IDs		O14657	B5B2S0 B5B2S1 Q12968
PDB IDs			2XRW 2XS0
Enriched GO Terms of Interacting Partners?
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