NFATC3 and CALB2

		NFATC3	CALB2
Description		nuclear factor of activated T cells 3	calbindin 2
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Cytosol	Nucleus Cytosol Gap Junction Dendrite Stereocilium Cuticular Plate Neuron Projection Terminal Bouton Synapse Synaptic Membrane Parallel Fiber To Purkinje Cell Synapse
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding	Calcium Ion Binding Calcium Ion Binding Involved In Regulation Of Presynaptic Cytosolic Calcium Ion Concentration
	Biological Process	Cytokine Production Regulation Of Transcription By RNA Polymerase II Inflammatory Response Calcineurin-NFAT Signaling Cascade Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Pri-miRNA Transcription By RNA Polymerase II Negative Regulation Of Vascular Associated Smooth Muscle Cell Differentiation	Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Regulation Of Long-term Synaptic Potentiation
Pathways		Calcineurin activates NFAT Calcineurin activates NFAT FCERI mediated Ca+2 mobilization CLEC7A (Dectin-1) induces NFAT activation
Drugs			Calcium citrate Calcium Phosphate Calcium levulinate Calcium phosphate dihydrate
Diseases
GWAS		Chronotype ( 30696823) Estimated glomerular filtration rate ( 31015462) Fasting glucose ( 33402679) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656) Serum alkaline phosphatase levels ( 33547301) Urate levels ( 31578528)	Bipolar disorder ( 34099189) Body mass index ( 30271922) General risk tolerance (MTAG) ( 30643258) Mood instability ( 31168069) Risk-taking tendency (4-domain principal component model) ( 30643258) Self-reported risk-taking behaviour ( 30271922)
Interacting Genes		13 interacting genes: CALB2 CDK6 CELSR2 CSNK1A1 FOS KCNJ3 MAPK8 MAPK9 MYOCD SEC24A SNX20 TOR1B TTF1	6 interacting genes: CFDP1 CIAO2B IST1 KRT1 NFATC3 TUBA4A
Entrez ID		4775	794
HPRD ID		04077	00230
Ensembl ID		ENSG00000072736	ENSG00000172137
Uniprot IDs		B5B2S0 B5B2S1 Q12968	A0A140VK08 A6NER6 P22676
PDB IDs		2XRW 2XS0
Enriched GO Terms of Interacting Partners?
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