SERP1 and AQP8

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SERP1	AQP8
Description		stress associated endoplasmic reticulum protein 1	aquaporin 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Ribosome Cytoplasmic Microtubule Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Mitochondrial Membrane Apical Part Of Cell
	Molecular Function	Protein Binding	Protein Binding Water Channel Activity
	Biological Process	Skeletal System Development Glucose Metabolic Process Cellular Protein Modification Process Protein Glycosylation Plasma Membrane Organization Post-embryonic Development Multicellular Organism Aging Protein Transport Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Insulin Secretion Positive Regulation Of Translation Positive Regulation Of Organ Growth Muscle Organ Morphogenesis Positive Regulation Of Growth Hormone Secretion	Water Transport Transmembrane Transport Cellular Response To CAMP
Pathways		XBP1(S) activates chaperone genes Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	Detoxification of Reactive Oxygen Species Passive transport by Aquaporins
Drugs
Diseases
GWAS		Academic attainment (English) ( 33594131)	Clozapine-induced agranulocytosis/granulocytopenia in treatment-resistant schizophrenia ( 27400856)
Interacting Genes		53 interacting genes: ACAD11 ALG3 APH1A APP AQP6 AQP8 BIK BSCL2 CANX CD74 CD79A CRB3 CYBRD1 EBP FAM174A FAM209A FAM210B FRMD3 GJB3 GJB5 GKN1 GPR37L1 GPX8 HSD17B13 IL3RA JAGN1 KCNF1 KIR3DL3 LHFPL5 LMNA MFSD14B MTIF3 PLPPR1 REEP4 SAR1A SCNN1A SCNN1G SEC11C SEC61A1 SEC61B SLC10A6 SLC22A1 SLC22A2 SLC35C2 SSMEM1 STX1A STX2 STX4 TLCD4 TMEM14B TMEM52B TMEM79 TNFRSF9	6 interacting genes: CYBC1 PLP2 PLPP6 SERP1 STX12 TMEM120B
Entrez ID		27230	343
HPRD ID		18037	04778
Ensembl ID		ENSG00000120742	ENSG00000103375
Uniprot IDs		Q9Y6X1	O94778
PDB IDs
Enriched GO Terms of Interacting Partners?
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