SERP1 and GJB3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SERP1	GJB3
Description		stress associated endoplasmic reticulum protein 1	gap junction protein beta 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Ribosome Cytoplasmic Microtubule Integral Component Of Membrane	Cytoplasm Gap Junction Connexin Complex Integral Component Of Membrane Cell Junction Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	Gap Junction Channel Activity Protein Binding
	Biological Process	Skeletal System Development Glucose Metabolic Process Cellular Protein Modification Process Protein Glycosylation Plasma Membrane Organization Post-embryonic Development Multicellular Organism Aging Protein Transport Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Insulin Secretion Positive Regulation Of Translation Positive Regulation Of Organ Growth Muscle Organ Morphogenesis Positive Regulation Of Growth Hormone Secretion	In Utero Embryonic Development Placenta Development Cell-cell Signaling Spermatogenesis Skin Development Transmembrane Transport Cellular Response To Retinoic Acid
Pathways		XBP1(S) activates chaperone genes Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	Gap junction assembly
Drugs
Diseases
GWAS		Academic attainment (English) ( 33594131)	Intraocular pressure ( 30591961) Triglyceride levels x thiazide or thiazide-like diuretics use interaction ( 31806883)
Interacting Genes		53 interacting genes: ACAD11 ALG3 APH1A APP AQP6 AQP8 BIK BSCL2 CANX CD74 CD79A CRB3 CYBRD1 EBP FAM174A FAM209A FAM210B FRMD3 GJB3 GJB5 GKN1 GPR37L1 GPX8 HSD17B13 IL3RA JAGN1 KCNF1 KIR3DL3 LHFPL5 LMNA MFSD14B MTIF3 PLPPR1 REEP4 SAR1A SCNN1A SCNN1G SEC11C SEC61A1 SEC61B SLC10A6 SLC22A1 SLC22A2 SLC35C2 SSMEM1 STX1A STX2 STX4 TLCD4 TMEM14B TMEM52B TMEM79 TNFRSF9	16 interacting genes: BTN2A2 CNST COMT ELAVL1 GIMAP5 IGFBP5 LAT LHFPL5 MFSD11 RPRM SERP1 TJP1 TMEM97 TMUB2 TRARG1 TUBD1
Entrez ID		27230	2707
HPRD ID		18037	04505
Ensembl ID		ENSG00000120742	ENSG00000188910
Uniprot IDs		Q9Y6X1	A0A654ICK0 O75712
PDB IDs
Enriched GO Terms of Interacting Partners?
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