BEX3 and ING5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		BEX3	ING5
Description		brain expressed X-linked 3	inhibitor of growth family member 5
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Histone Acetyltransferase Complex Nucleus Nucleoplasm Chromosome MOZ/MORF Histone Acetyltransferase Complex
	Molecular Function	Signaling Receptor Binding Nerve Growth Factor Receptor Binding Protein Binding Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process Identical Protein Binding Metal Ion Binding	Chromatin Binding Protein Binding Methylated Histone Binding Metal Ion Binding
	Biological Process	Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Signal Transduction Multicellular Organism Development Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors	DNA Replication Regulation Of Transcription, DNA-templated Protein Acetylation Negative Regulation Of Cell Population Proliferation Positive Regulation Of Apoptotic Process Histone H3 Acetylation Histone H4 Acetylation Histone H3-K14 Acetylation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Growth Positive Regulation Of Apoptotic Signaling Pathway
Pathways		NADE modulates death signalling	HATs acetylate histones Regulation of TP53 Activity through Acetylation
Drugs
Diseases
GWAS			Asthma ( 31959851) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Platelet distribution width ( 32888494)
Interacting Genes		42 interacting genes: AIMP2 AKAP8L BFSP2 CACYBP CBY2 CCDC116 CCDC85B CTNNBL1 DIABLO EMILIN1 ENKD1 FSD2 GOLGA8EP GOLGA8F ING4 ING5 KRT34 MCCD1 MDFI MIF MNAT1 NECAB2 NGFR NTRK3 PTPN13 S100A1 S100Z SIVA1 SMARCD1 SMPD1 TACC3 TRAF1 TRAF2 TRAF3 TRAF4 TRAF5 TRAF6 TSNAX USHBP1 VTA1 YWHAE ZNF417	45 interacting genes: APC APLP1 ARFIP2 BARD1 BEX3 C3orf62 CBY2 CCDC33 CCHCR1 CDCA7L CDK2 CDKN1A CEP126 CEP44 DEUP1 EP300 FAM118B GCSH GGA1 GRIPAP1 HAP1 HGS HTT ICA1 IKZF3 KRT40 KRTAP10-7 KXD1 MBIP MCM6 MEST NAV2 ODF2 PCM1 PRMT5 RCOR3 SMARCE1 SUOX TADA3 TAF1D THAP6 TP53 TRIML2 VIM WASF1
Entrez ID		27018	84289
HPRD ID		02291	16348
Ensembl ID		ENSG00000166681	ENSG00000168395
Uniprot IDs		Q00994	A0A1B0GW41 Q8WYH8
PDB IDs		1SA6	3C6W 5ME8 5MTO
Enriched GO Terms of Interacting Partners?
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