AKAP8L and LBR

Number of citations of the paper that reports this interaction (PubMedID 11034899)
25

Data Source:
HPRD (in vivo)

		AKAP8L	LBR
Description		A-kinase anchoring protein 8 like	lamin B receptor
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Cytoplasm Nuclear Matrix PML Body Nuclear Speck Ribonucleoprotein Complex	Nucleus Nuclear Envelope Nuclear Inner Membrane Integral Component Of Nuclear Inner Membrane Cytoplasm Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Nuclear Membrane
	Molecular Function	DNA Binding RNA Binding Protein Binding Lamin Binding DEAD/H-box RNA Helicase Binding Protein Kinase A Regulatory Subunit Binding Histone Deacetylase Binding Metal Ion Binding	DNA Binding RNA Binding Protein Binding Lamin Binding Oxidoreductase Activity, Acting On The CH-CH Group Of Donors Delta14-sterol Reductase Activity Chromo Shadow Domain Binding NADPH Binding
	Biological Process	MRNA Processing Mitotic Chromosome Condensation RNA Splicing Regulation Of MRNA Export From Nucleus Positive Regulation Of Histone Deacetylation Regulation Of Histone Phosphorylation Cell Cycle G2/M Phase Transition Positive Regulation Of Transcription By RNA Polymerase II Nuclear Membrane Disassembly	Cholesterol Biosynthetic Process Sterol Biosynthetic Process Neutrophil Differentiation
Pathways			Cholesterol biosynthesis Initiation of Nuclear Envelope (NE) Reformation RHOA GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOG GTPase cycle RAC3 GTPase cycle Regulation of MECP2 expression and activity
Drugs
Diseases
GWAS		Red blood cell count ( 32888494)	Delirium ( 29631748) LDL cholesterol levels in HIV infection ( 33109212) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		67 interacting genes: ABI2 ACTN2 AP1M1 ASF1B ATPAF2 BEX3 BRME1 CARHSP1 CATSPER1 CCDC120 CCDC24 CDC6 CNNM3 CREB5 CSTF2 CSTF2T DGCR6 DHX9 DMRT3 EMD ENKD1 EPHX3 FAM214B FOXD4 GPANK1 GPS2 HEMK1 HGS HSF4 ICAM4 IL18R1 INCA1 KPRP LAGE3 LBR MYOZ1 MYPOP OR7A17 PATZ1 PCDHB14 PEF1 PITX1 PLEKHN1 PPP1R32 PRKAA2 PRKACA PRPF40A RAMAC RASAL3 RTP5 RUSC1 SAMD4A SAXO1 SH3RF2 SNRPC TEKT4 TEKT5 TENT5B TFAP2D TIAL1 TLE5 TMPO TMSB4X TRIB3 TSGA10IP WDR25 ZNF366	13 interacting genes: AKAP8L CBX3 CBX5 CD81 FNBP4 H4C14 LMNB1 MECP2 PRM1 SFTPD SRPK1 SRPK2 YWHAG
Entrez ID		26993	3930
HPRD ID		10641	02488
Ensembl ID		ENSG00000011243	ENSG00000143815
Uniprot IDs		Q9ULX6	Q14739
PDB IDs			2DIG
Enriched GO Terms of Interacting Partners?
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