AKAP8L and CSTF2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		AKAP8L	CSTF2
Description		A-kinase anchoring protein 8 like	cleavage stimulation factor subunit 2
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Cytoplasm Nuclear Matrix PML Body Nuclear Speck Ribonucleoprotein Complex	Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex Nuclear Body Cleavage Body
	Molecular Function	DNA Binding RNA Binding Protein Binding Lamin Binding DEAD/H-box RNA Helicase Binding Protein Kinase A Regulatory Subunit Binding Histone Deacetylase Binding Metal Ion Binding	RNA Binding MRNA Binding Protein Binding
	Biological Process	MRNA Processing Mitotic Chromosome Condensation RNA Splicing Regulation Of MRNA Export From Nucleus Positive Regulation Of Histone Deacetylation Regulation Of Histone Phosphorylation Cell Cycle G2/M Phase Transition Positive Regulation Of Transcription By RNA Polymerase II Nuclear Membrane Disassembly	MRNA Polyadenylation Pre-mRNA Cleavage Required For Polyadenylation Cellular Response To Nerve Growth Factor Stimulus
Pathways			tRNA processing in the nucleus mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS		Red blood cell count ( 32888494)
Interacting Genes		67 interacting genes: ABI2 ACTN2 AP1M1 ASF1B ATPAF2 BEX3 BRME1 CARHSP1 CATSPER1 CCDC120 CCDC24 CDC6 CNNM3 CREB5 CSTF2 CSTF2T DGCR6 DHX9 DMRT3 EMD ENKD1 EPHX3 FAM214B FOXD4 GPANK1 GPS2 HEMK1 HGS HSF4 ICAM4 IL18R1 INCA1 KPRP LAGE3 LBR MYOZ1 MYPOP OR7A17 PATZ1 PCDHB14 PEF1 PITX1 PLEKHN1 PPP1R32 PRKAA2 PRKACA PRPF40A RAMAC RASAL3 RTP5 RUSC1 SAMD4A SAXO1 SH3RF2 SNRPC TEKT4 TEKT5 TENT5B TFAP2D TIAL1 TLE5 TMPO TMSB4X TRIB3 TSGA10IP WDR25 ZNF366	48 interacting genes: ABHD11 AKAP8L ANKRD10 APP ATP23 BAG6 CDSN CEACAM6 CEP126 CHD3 CNOT2 CSTF3 CTBP2 DDX1 ECH1 EEF1G ELP1 ERG28 FAM168B FEZ1 HDHD3 HGS IMMT INCA1 KAT5 METTL15 METTL27 MIR19A MIR92A2 POLR2A POU6F2 PPP1R32 PRDM6 RFX6 SPAG8 SS18L1 STH SUB1 SYMPK TFG TLE3 TLE5 TSC1 UBQLN1 UBQLN4 UFSP1 USP54 ZNF341
Entrez ID		26993	1478
HPRD ID		10641	02652
Ensembl ID		ENSG00000011243	ENSG00000101811
Uniprot IDs		Q9ULX6	B3V096 B4DUD5 E7EWR4 P33240
PDB IDs			1P1T 2J8P 6Q2I 6TZE
Enriched GO Terms of Interacting Partners?
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