OPLAH and GK

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		OPLAH	GK
Description		5-oxoprolinase, ATP-hydrolysing	glycerol kinase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol	Mitochondrion Mitochondrial Outer Membrane Cytosol Extracellular Exosome
	Molecular Function	Protein Binding ATP Binding 5-oxoprolinase (ATP-hydrolyzing) Activity Identical Protein Binding	Glycerol Kinase Activity Protein Binding ATP Binding Phosphotransferase Activity, Alcohol Group As Acceptor
	Biological Process	Glutathione Metabolic Process	Glycerol Metabolic Process Triglyceride Metabolic Process Phosphorylation Triglyceride Biosynthetic Process Glycerol Catabolic Process Glycerol-3-phosphate Biosynthetic Process
Pathways		Glutathione synthesis and recycling Defective OPLAH causes OPLAHD	Triglyceride biosynthesis
Drugs		Glutamic acid
Diseases
GWAS		Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Blood metabolite levels ( 24816252) Mean spheric corpuscular volume ( 32888494) Metabolic traits ( 21886157) Serum metabolite concentrations in chronic kidney disease ( 33838163) Serum metabolite levels ( 33031748 23093944)	Cardiovascular risk factors (age interaction) ( 20838585)
Interacting Genes		5 interacting genes: GK HOXA1 POU6F2 TPK1 ZNF451	11 interacting genes: AOX1 APCS CLPTM1L CYP3A4 EIF4G1 FBXO28 GPD1 IPO13 NR4A1 OPLAH RXRA
Entrez ID		26873	2710
HPRD ID		14880	08363
Ensembl ID		ENSG00000178814	ENSG00000198814
Uniprot IDs		O14841	B4DH54 P32189
PDB IDs
Enriched GO Terms of Interacting Partners?
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