GDI2 and RAB11A

Number of citations of the paper that reports this interaction (PubMedID 10512627)
20

Data Source:
HPRD (in vitro)

		GDI2	RAB11A
Description		GDP dissociation inhibitor 2	RAB11A, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Focal Adhesion Membrane Vesicle Secretory Granule Lumen Azurophil Granule Lumen Synapse Extracellular Exosome	Spindle Pole Endosome Multivesicular Body Golgi Apparatus Trans-Golgi Network Centrosome Kinetochore Microtubule Cytosol Transport Vesicle Axon Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Vesicle Cleavage Furrow Protein-containing Complex Centriolar Satellite Intracellular Membrane-bounded Organelle Phagocytic Vesicle Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane Extracellular Exosome Schaffer Collateral - CA1 Synapse Postsynaptic Recycling Endosome Glutamatergic Synapse
	Molecular Function	RNA Binding Rab GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding Small GTPase Binding	GTPase Activity G Protein Activity Protein Binding GTP Binding Microtubule Binding Syntaxin Binding Myosin V Binding
	Biological Process	Signal Transduction Small GTPase Mediated Signal Transduction Protein Transport Vesicle-mediated Transport Regulation Of Catalytic Activity	Exocytosis Mitotic Metaphase Plate Congression Positive Regulation Of Epithelial Cell Migration Regulation Of Multivesicular Body Size Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Vesicle-mediated Transport Astral Microtubule Organization Neuron Projection Development Melanosome Transport Regulation Of Cytokinesis Protein Localization To Cell Surface Multivesicular Body Assembly Positive Regulation Of Axon Extension Regulation Of Long-term Neuronal Synaptic Plasticity Plasma Membrane To Endosome Transport Regulation Of Protein Transport Establishment Of Vesicle Localization Regulation Of Vesicle-mediated Transport Establishment Of Protein Localization To Organelle Protein Localization To Plasma Membrane Establishment Of Protein Localization To Membrane Mitotic Spindle Assembly Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Vesicle-mediated Transport In Synapse Amyloid-beta Clearance By Transcytosis Positive Regulation Of Protein Localization To Plasma Membrane Exosomal Secretion
Pathways		Neutrophil degranulation RAB GEFs exchange GTP for GDP on RABs	Translocation of SLC2A4 (GLUT4) to the plasma membrane Vasopressin regulates renal water homeostasis via Aquaporins Anchoring of the basal body to the plasma membrane VxPx cargo-targeting to cilium TBC/RABGAPs RAB geranylgeranylation
Drugs			5'-Guanosine-Diphosphate-Monothiophosphate Guanosine-5'-Diphosphate
Diseases
GWAS		Blood protein levels ( 30072576) Cutaneous malignant melanoma ( 32341527) Osteosarcoma ( 23727862)	Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Mean corpuscular hemoglobin ( 29403010 32888494 27863252) Mean corpuscular hemoglobin concentration ( 29403010) Mean corpuscular volume ( 29403010 32888494 27863252) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Red blood cell count ( 27863252) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		11 interacting genes: GATA3 GLRA2 HSPB1 LINC01554 OGT RAB11A RAB2A RAB4A RAB5A RAB8A RAB9A	33 interacting genes: ARF6 CHMP1B CHMP3 DTNBP1 GDI2 IKBKG KAT2B MYO5A MYO5B OPTN PPP2R1A PPP2R1B PSEN1 PSEN2 PTGIR RAB11FIP1 RAB11FIP2 RAB11FIP3 RAB11FIP4 RAB11FIP5 RAB13 RAB3IL1 RAB3IP RAB8A RABGGTB RCHY1 RELA SEC13 SMAD6 STX4 TBXA2R TDP2 WDR44
Entrez ID		2665	8766
HPRD ID		02863	05715
Ensembl ID		ENSG00000057608	ENSG00000103769
Uniprot IDs		P50395 Q6IAT1	A0A024R5Z8 P62491
PDB IDs			1OIV 1OIW 1OIX 1YZK 2D7C 2GZD 2GZH 2HV8 4C4P 4D0L 4D0M 4LWZ 4LX0 4UJ3 4UJ4 4UJ5 5C46 5C4G 5EUQ 5EZ5 5FBL 5FBQ 5FBR 5FBV 5FBW 5JCZ 6DJL 6IXV
Enriched GO Terms of Interacting Partners?
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