GDI2 and RAB2A

Number of citations of the paper that reports this interaction (PubMedID 10512627)
20

Data Source:
BioGRID (proximity labelling technology)
HPRD (in vitro)

		GDI2	RAB2A
Description		GDP dissociation inhibitor 2	RAB2A, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Focal Adhesion Membrane Vesicle Secretory Granule Lumen Azurophil Granule Lumen Synapse Extracellular Exosome	Golgi Membrane Nucleus Lysosomal Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Melanosome Extracellular Exosome
	Molecular Function	RNA Binding Rab GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding Small GTPase Binding	GTPase Activity Protein Binding GTP Binding GDP Binding
	Biological Process	Signal Transduction Small GTPase Mediated Signal Transduction Protein Transport Vesicle-mediated Transport Regulation Of Catalytic Activity	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Protein Transport
Pathways		Neutrophil degranulation RAB GEFs exchange GTP for GDP on RABs	Golgi Cisternae Pericentriolar Stack Reorganization RAB geranylgeranylation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Cutaneous malignant melanoma ( 32341527) Osteosarcoma ( 23727862)	Aspartate aminotransferase levels ( 33547301) Autoimmune thyroid disease ( 32581359) Estimated glomerular filtration rate ( 31152163) Low density lipoprotein cholesterol levels ( 32154731) Neutrophil count ( 32888494) Systemic sclerosis ( 31672989) Total cholesterol levels ( 29083408)
Interacting Genes		11 interacting genes: GATA3 GLRA2 HSPB1 LINC01554 OGT RAB11A RAB2A RAB4A RAB5A RAB8A RAB9A	30 interacting genes: ASPH BLZF1 CBFB CCDC125 CFL2 CPA4 FAM114A1 FAM114A2 FAM71A FAM71C FAM71F2 FRMD1 GAPDH GDI2 GOLGA2 GORASP2 HES6 ICA1 MAPK6 MAPKAPK3 PMAIP1 PRKCI RBSN RGS2 RP1 SGSM2 STAMBPL1 TBC1D25 TMEM70 TRIM7
Entrez ID		2665	5862
HPRD ID		02863	01539
Ensembl ID		ENSG00000057608	ENSG00000104388
Uniprot IDs		P50395 Q6IAT1	A0A024R7V6 P61019
PDB IDs			1Z0A
Enriched GO Terms of Interacting Partners?
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