GDI1 and RAB6A

Number of citations of the paper that reports this interaction (PubMedID 8175798)
10

Data Source:
HPRD (in vitro)

		GDI1	RAB6A
Description		GDP dissociation inhibitor 1	RAB6A, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Axon Midbody Protein-containing Complex Neuronal Cell Body Myelin Sheath	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Endomembrane System Membrane Secretory Granule Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Extracellular Exosome Endosome To Plasma Membrane Transport Vesicle
	Molecular Function	GDP-dissociation Inhibitor Activity Rab GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding Small GTPase Binding	GTPase Activity Protein Binding GTP Binding Protein Domain Specific Binding Myosin V Binding
	Biological Process	Signal Transduction Protein Transport Vesicle-mediated Transport Rab Protein Signal Transduction Positive Regulation Of Axon Extension Negative Regulation Of Axonogenesis Regulation Of Catalytic Activity Response To Calcium Ion Negative Regulation Of Protein Targeting To Membrane	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Peptidyl-cysteine Methylation Antigen Processing And Presentation Protein Localization To Golgi Apparatus Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Minus-end-directed Organelle Transport Along Microtubule
Pathways		RAB GEFs exchange GTP for GDP on RABs	Pre-NOTCH Processing in Golgi Neutrophil degranulation COPI-independent Golgi-to-ER retrograde traffic Retrograde transport at the Trans-Golgi-Network TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS			Dimensional psychopathology (Cognitive) ( 29496196) Obesity-related traits ( 23251661)
Interacting Genes		18 interacting genes: CDC42 EPB41 GNL1 IRAK1 LNX1 OGT PACS1 PSEN1 RAB1B RAB27A RAB3B RAB6A RAB9A RABAC1 RAC2 RHOH TK1 UBQLN4	22 interacting genes: BICD1 BICD2 CHM CHML DCTN1 ERC1 FKBP2 GDI1 GOLGA1 GOLGA2 GOLGA4 GORAB KIF20A OCRL PMM1 RAB7A RABAC1 RABGAP1 RABGGTB SHANK2 SYTL5 TMF1
Entrez ID		2664	5870
HPRD ID		02114	01543
Ensembl ID		ENSG00000203879	ENSG00000175582
Uniprot IDs		A0A0S2Z3X8 P31150	A0A024R5H8 A0A024R5J5 P20340 Q53ET8
PDB IDs			1YZQ 2GIL 3BBP 3CWZ 4DKX 5LEF
Enriched GO Terms of Interacting Partners?
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