AATF and NGDN

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, proximity labelling technology)

		AATF	NGDN
Description		apoptosis antagonizing transcription factor	neuroguidin
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Regulator Complex Nucleolus Cytoplasm Golgi Apparatus	Chromosome, Centromeric Region Nucleoplasm Nucleolus Mitochondrion Filopodium Axon Dendrite Small-subunit Processome
	Molecular Function	RNA Binding Protein Binding Protein Kinase Binding Leucine Zipper Domain Binding Tau Protein Binding	RNA Binding Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Cellular Response To DNA Damage Stimulus Cell Adhesion Regulation Of Mitotic Cell Cycle Negative Regulation Of Superoxide Anion Generation Embryonic Cleavage Ribosome Biogenesis Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Reactive Oxygen Species Metabolic Process Negative Regulation Of Apoptotic Signaling Pathway	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Regulation Of Translation
Pathways		NRAGE signals death through JNK
Drugs
Diseases
GWAS		Body mass index ( 26426971) Erectile dysfunction ( 30583798) Obesity-related traits ( 23251661) Thyroid volume in Hashimotoâ€™s thyroiditis ( 32019955)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
Interacting Genes		34 interacting genes: ATM ATR AURKA CCL5 CCL7 CHEK1 CHEK2 CPD DAPK3 DAZAP2 EFNB3 FBXO7 HIPK2 LDOC1 LZTR1 MAPT MPHOSPH6 MYCBP2 MYO1D NEDD4L NGDN NOS2 NPTN PALS2 PAWR PCBD2 POLR2J RB1 RELA SMAD3 SP1 SS18L1 TSG101 ZNF468	10 interacting genes: AATF CSNK2B LRP10 MFAP1 NOM1 OR10G2 OR10G3 OR4E2 SRPK2 SUPT16H
Entrez ID		26574	25983
HPRD ID		12236	10708
Ensembl ID		ENSG00000275700	ENSG00000129460
Uniprot IDs		Q9NY61	Q8NEJ9
PDB IDs		5W6A
Enriched GO Terms of Interacting Partners?
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