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AATF

Description apoptosis antagonizing transcription factor
Image
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Transcription Regulator Complex
  • Nucleolus
  • Cytoplasm
  • Golgi Apparatus
Molecular Function
  • RNA Binding
  • Protein Binding
  • Protein Kinase Binding
  • Leucine Zipper Domain Binding
  • Tau Protein Binding
Biological Process
  • Regulation Of Transcription By RNA Polymerase II
  • Cellular Response To DNA Damage Stimulus
  • Cell Adhesion
  • Regulation Of Mitotic Cell Cycle
  • Negative Regulation Of Superoxide Anion Generation
  • Embryonic Cleavage
  • Ribosome Biogenesis
  • Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process
  • Negative Regulation Of Apoptotic Process
  • Positive Regulation Of Transcription By RNA Polymerase II
  • Negative Regulation Of Reactive Oxygen Species Metabolic Process
  • Negative Regulation Of Apoptotic Signaling Pathway
Pathways
  • NRAGE signals death through JNK
Drugs
Diseases
GWAS
  • Body mass index ( 26426971)
  • Erectile dysfunction ( 30583798)
  • Obesity-related traits ( 23251661)
  • Thyroid volume in Hashimoto’s thyroiditis ( 32019955)
Interacting Genes 34 interacting genes: ATM ATR AURKA CCL5 CCL7 CHEK1 CHEK2 CPD DAPK3 DAZAP2 EFNB3 FBXO7 HIPK2 LDOC1 LZTR1 MAPT MPHOSPH6 MYCBP2 MYO1D NEDD4L NGDN NOS2 NPTN PALS2 PAWR PCBD2 POLR2J RB1 RELA SMAD3 SP1 SS18L1 TSG101 ZNF468
Entrez ID 26574
HPRD ID 12236
Ensembl ID ENSG00000275700
Uniprot IDs Q9NY61
PDB IDs 5W6A
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025