B3GAT3 and SEC22B

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		B3GAT3	SEC22B
Description		beta-1,3-glucuronyltransferase 3	SEC22 homolog B, vesicle trafficking protein
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GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Cis-Golgi Network Membrane Integral Component Of Membrane Extracellular Exosome	Golgi Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Synaptic Vesicle ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane Transport Vesicle COPI-coated Vesicle Phagocytic Vesicle Membrane SNARE Complex Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Melanosome
	Molecular Function	Protein Binding Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase Activity Glucuronosyltransferase Activity Metal Ion Binding Protein Phosphatase Activator Activity	SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Carbohydrate Metabolic Process Glycosaminoglycan Biosynthetic Process Protein Glycosylation Heparan Sulfate Proteoglycan Biosynthetic Process Positive Regulation Of Catalytic Activity Chondroitin Sulfate Proteoglycan Biosynthetic Process Dermatan Sulfate Proteoglycan Biosynthetic Process Positive Regulation Of Intracellular Protein Transport	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Protein Transport Positive Regulation Of Protein Catabolic Process Vesicle Fusion With Golgi Apparatus Negative Regulation Of Autophagosome Assembly
Pathways		A tetrasaccharide linker sequence is required for GAG synthesis Defective B3GAT3 causes JDSSDHD	ER-Phagosome pathway COPII-mediated vesicle transport Cargo concentration in the ER COPI-dependent Golgi-to-ER retrograde traffic
Drugs		UDP-alpha-D-glucuronic acid Uridine-5'-Diphosphate
Diseases
GWAS		Blood protein levels ( 29875488) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Iris color (L* coordinate) ( 30895295)
Interacting Genes		5 interacting genes: CCR2 CCR4 GPR35 HNRNPD SEC22B	56 interacting genes: ABHD16A AIG1 AQP6 B3GAT3 CD160 CD79A CERS6 CLDN7 CLRN1 CPLX4 CREB3 CREB3L1 DPM3 EBP ELOVL4 ERGIC3 FAM174A FAM209A FCER1G FNDC9 GJA8 GJB5 GJB6 GORAB GPR152 GPX8 HIBADH HSD17B13 IFNGR2 JAGN1 KIR2DL3 LHFPL1 LHFPL5 LMNA MFF MFSD5 MGST2 MGST3 MMGT1 MRPS18B NDUFAF2 REEP4 RELL2 RHBDD1 SERINC2 SLC35C2 STX1A STX2 STX4 STX5 TLCD4 TM4SF19 TMEM139 TMEM167B TMEM229B TMEM86B
Entrez ID		26229	9554
HPRD ID		07564	04939
Ensembl ID		ENSG00000149541	ENSG00000265808
Uniprot IDs		G3V150 O94766 Q5U676	O75396
PDB IDs		1FGG 1KWS 3CU0	2NUP 2NUT 3EGD 3EGX
Enriched GO Terms of Interacting Partners?
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