B3GAT3

Description		beta-1,3-glucuronyltransferase 3
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GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Cis-Golgi Network Membrane Integral Component Of Membrane Extracellular Exosome
	Molecular Function	Protein Binding Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase Activity Glucuronosyltransferase Activity Metal Ion Binding Protein Phosphatase Activator Activity
	Biological Process	Carbohydrate Metabolic Process Glycosaminoglycan Biosynthetic Process Protein Glycosylation Heparan Sulfate Proteoglycan Biosynthetic Process Positive Regulation Of Catalytic Activity Chondroitin Sulfate Proteoglycan Biosynthetic Process Dermatan Sulfate Proteoglycan Biosynthetic Process Positive Regulation Of Intracellular Protein Transport
Pathways		A tetrasaccharide linker sequence is required for GAG synthesis Defective B3GAT3 causes JDSSDHD
Drugs		UDP-alpha-D-glucuronic acid Uridine-5'-Diphosphate
Diseases
GWAS		Blood protein levels ( 29875488) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		5 interacting genes: CCR2 CCR4 GPR35 HNRNPD SEC22B
Entrez ID		26229
HPRD ID		07564
Ensembl ID		ENSG00000149541
Uniprot IDs		G3V150 O94766 Q5U676
PDB IDs		1FGG 1KWS 3CU0
Enriched GO Terms of Interacting Partners?
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