PYGO1 and BCL9

Number of citations of the paper that reports this interaction (PubMedID 11955446)
208

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		PYGO1	BCL9
Description		pygopus family PHD finger 1	BCL9 transcription coactivator
Image
GO Annotations	Cellular Component	Nucleoplasm	Nucleoplasm Cis-Golgi Network Beta-catenin-TCF Complex
	Molecular Function	Protein Binding Methylated Histone Binding Metal Ion Binding	Transcription Coactivator Activity Protein Binding Beta-catenin Binding
	Biological Process	Kidney Development Hematopoietic Progenitor Cell Differentiation Spermatid Nucleus Differentiation Protein Localization To Nucleus Positive Regulation Of Transcription By RNA Polymerase II Canonical Wnt Signaling Pathway	Myotube Differentiation Involved In Skeletal Muscle Regeneration Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Somatic Stem Cell Population Maintenance Skeletal Muscle Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Canonical Wnt Signaling Pathway
Pathways		Formation of the beta-catenin:TCF transactivating complex Deactivation of the beta-catenin transactivating complex	Formation of the beta-catenin:TCF transactivating complex Deactivation of the beta-catenin transactivating complex
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545)	Adult body size ( 32376654) Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU) ( 24025145) Schizophrenia (negative symptoms) ( 23382809) Triglyceride change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Type 2 diabetes ( 25760438)
Interacting Genes		6 interacting genes: BCL9 CARM1 CTNNB1 LENG8 PRMT6 SPTBN1	4 interacting genes: CTNNB1 PYGO1 PYGO2 USP9X
Entrez ID		26108	607
HPRD ID		06064	04000
Ensembl ID		ENSG00000171016	ENSG00000116128
Uniprot IDs		Q9Y3Y4	A0A024QYY4 O00512 Q1JQ81
PDB IDs		2VP7 2VPB 2VPD 2VPE 2VPG	2GL7 2VP7 2VPB 2VPD 2VPE 2VPG 3SL9
Enriched GO Terms of Interacting Partners?
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