RNF167 and ACTA1

Number of citations of the paper that reports this interaction (PubMedID 23414517)
13

Data Source:
BioGRID (two hybrid)

		RNF167	ACTA1
Description		ring finger protein 167	actin alpha 1, skeletal muscle
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endomembrane System Integral Component Of Membrane	Stress Fiber Extracellular Space Cytosol Striated Muscle Thin Filament Dynactin Complex Actin Filament Actin Cytoskeleton Sarcomere Lamellipodium Filopodium Cell Body Extracellular Exosome Blood Microparticle
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity	Structural Constituent Of Cytoskeleton Protein Binding ATP Binding Myosin Binding ADP Binding
	Biological Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cell Cycle	Muscle Contraction Response To Mechanical Stimulus Response To Extracellular Stimulus Response To Lithium Ion Positive Regulation Of Gene Expression Skeletal Muscle Thin Filament Assembly Skeletal Muscle Fiber Adaptation Response To Steroid Hormone Skeletal Muscle Fiber Development Cellular Response To Organonitrogen Compound Mesenchyme Migration
Pathways			Striated Muscle Contraction
Drugs			Latrunculin A Sucrose Ulapualide A Kabiramide C Jaspisamide A Tmr 1-Methylhistidine Phosphoaminophosphonic Acid-Adenylate Ester Aplyronine A Reidispongiolide A Reidispongiolide C Sphinxolide B Latrunculin B
Diseases
GWAS		Blood metabolite levels ( 24816252) Keratoconus ( 33649486) Platelet count ( 32888494) Plateletcrit ( 32888494)
Interacting Genes		18 interacting genes: ACTA1 AFG3L2 ATP2A1 CAPN3 MYH7 SLC22A18 SUMO1 TMEM97 TTN UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2K UBE2N UBE2W	114 interacting genes: ABL1 ABRA ACTR10 ACTR1B ADSS2 AFAP1 AIF1 AJUBA AMOT ANXA2 BIN1 CCIN CCT2 CCT4 CCT5 CFL1 CLIC5 CNN1 CORO2B COTL1 CTNND1 CTTN CYFIP1 CYTH1 DHX9 DLG1 DMD DNASE1 DNMBP DTNA DUX4L9 EGFR EPB41 EPB41L2 EPS8 FGD4 FHOD1 FSCN1 GAS2 GAS7 GC GSN HCLS1 HDAC4 HIP1R HSPB2 HTRA2 IQGAP1 ITGA2 ITPKA KIF23 KLHL20 LASP1 MACF1 MAP1A MAPT MIB2 MINPP1 MYL1 MYLK MYO10 MYO6 MYO7A MYO9B NEXN NR3C2 NRAP PAK1 PARVA PCYT1B PFDN1 PFN1 PHACTR1 PLD1 PPP1R9B PRKCA PRKCD PRKCE RAC1 RNF167 RPS6KB1 S100A1 S100A4 SCIN SMTN SNCA SORBS1 SPRR1A SPTA1 SPTAN1 SPTBN2 TAGLN TJP1 TLN1 TMSB4X TMSB4Y TNNI1 TNNI3 TNNI3K TP53 TPM2 TPM3 TRIM55 TRIM63 TTN UBC USP25 USP6NL UTRN VASP VAV1 VCL VIL1 XIRP1
Entrez ID		26001	58
HPRD ID		15261	00030
Ensembl ID		ENSG00000108523	ENSG00000143632
Uniprot IDs		I3L0L6 Q9H6Y7	P68133
PDB IDs
Enriched GO Terms of Interacting Partners?
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