DNAH1 and G3BP1

		DNAH1	G3BP1
Description		dynein axonemal heavy chain 1	G3BP stress granule assembly factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Axonemal Dynein Complex Microtubule Axoneme Dynein Complex Sperm Flagellum Inner Dynein Arm	Nucleus Cytoplasm Cytosol Focal Adhesion Cytoplasmic Stress Granule Perikaryon Ribonucleoprotein Complex
	Molecular Function	Microtubule Motor Activity ATP Binding Minus-end-directed Microtubule Motor Activity Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding	DNA Binding DNA Helicase Activity RNA Binding RNA Helicase Activity MRNA Binding Endonuclease Activity Protein Binding ATP Binding ATP Hydrolysis Activity DNA/RNA Helicase Activity
	Biological Process	Cilium Movement Microtubule-based Movement Sperm Axoneme Assembly Flagellated Sperm Motility Inner Dynein Arm Assembly Cilium-dependent Cell Motility	Ras Protein Signal Transduction Positive Regulation Of Type I Interferon Production DNA Duplex Unwinding Stress Granule Assembly Innate Immune Response Defense Response To Virus Positive Regulation Of Stress Granule Assembly Negative Regulation Of Canonical Wnt Signaling Pathway Nucleic Acid Phosphodiester Bond Hydrolysis
Pathways
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) Chronotype ( 30696823) Electroencephalogram traits ( 25387704) HDL cholesterol ( 30275531) Parkinson's disease ( 28892059) Schizophrenia ( 23974872) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Periventricular white matter hyperintensities ( 32517579) Platelet distribution width ( 32888494) Red cell distribution width ( 32888494)
Interacting Genes		7 interacting genes: ABHD14A G3BP1 GNL3 LIN7B POC1A RPP30 SEPSECS	17 interacting genes: APP CSK DNAH1 DTX1 EPHA8 FBXO25 HAND1 HMGXB3 IL7R LCK LINC01554 OGT PIN1 PPIA RASA1 SYNPO USP10
Entrez ID		25981	10146
HPRD ID		11790	06569
Ensembl ID		ENSG00000114841	ENSG00000145907
Uniprot IDs		A0A140VJI6 Q9P2D7	Q13283 Q5U0Q1 Q6ZP53
PDB IDs			3Q90 4FCJ 4FCM 4IIA 5FW5
Enriched GO Terms of Interacting Partners?
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