G3BP1 and DNAH1

		G3BP1	DNAH1
Description		G3BP stress granule assembly factor 1	dynein axonemal heavy chain 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Focal Adhesion Cytoplasmic Stress Granule Perikaryon Ribonucleoprotein Complex	Axonemal Dynein Complex Microtubule Axoneme Dynein Complex Sperm Flagellum Inner Dynein Arm
	Molecular Function	DNA Binding DNA Helicase Activity RNA Binding RNA Helicase Activity MRNA Binding Endonuclease Activity Protein Binding ATP Binding ATP Hydrolysis Activity DNA/RNA Helicase Activity	Microtubule Motor Activity ATP Binding Minus-end-directed Microtubule Motor Activity Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding
	Biological Process	Ras Protein Signal Transduction Positive Regulation Of Type I Interferon Production DNA Duplex Unwinding Stress Granule Assembly Innate Immune Response Defense Response To Virus Positive Regulation Of Stress Granule Assembly Negative Regulation Of Canonical Wnt Signaling Pathway Nucleic Acid Phosphodiester Bond Hydrolysis	Cilium Movement Microtubule-based Movement Sperm Axoneme Assembly Flagellated Sperm Motility Inner Dynein Arm Assembly Cilium-dependent Cell Motility
Pathways
Drugs
Diseases
GWAS		Periventricular white matter hyperintensities ( 32517579) Platelet distribution width ( 32888494) Red cell distribution width ( 32888494)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) Chronotype ( 30696823) Electroencephalogram traits ( 25387704) HDL cholesterol ( 30275531) Parkinson's disease ( 28892059) Schizophrenia ( 23974872) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		17 interacting genes: APP CSK DNAH1 DTX1 EPHA8 FBXO25 HAND1 HMGXB3 IL7R LCK LINC01554 OGT PIN1 PPIA RASA1 SYNPO USP10	7 interacting genes: ABHD14A G3BP1 GNL3 LIN7B POC1A RPP30 SEPSECS
Entrez ID		10146	25981
HPRD ID		06569	11790
Ensembl ID		ENSG00000145907	ENSG00000114841
Uniprot IDs		Q13283 Q5U0Q1 Q6ZP53	A0A140VJI6 Q9P2D7
PDB IDs		3Q90 4FCJ 4FCM 4IIA 5FW5
Enriched GO Terms of Interacting Partners?
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