PTPN23 and UBAP1

Number of citations of the paper that reports this interaction (PubMedID 21757351)
46

Data Source:
BioGRID (two hybrid, affinity chromatography technology, pull down, two hybrid, x-ray crystallography, unspecified method)

		PTPN23	UBAP1
Description		protein tyrosine phosphatase non-receptor type 23	ubiquitin associated protein 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Endosome Early Endosome Cytosol Nuclear Body Ciliary Basal Body Intracellular Membrane-bounded Organelle Extracellular Exosome	ESCRT I Complex Cytoplasm Cytosol Plasma Membrane Endosome Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding Protein Kinase Binding	Protein Binding Ubiquitin Binding
	Biological Process	Negative Regulation Of Epithelial Cell Migration Protein Transport Endocytic Recycling Peptidyl-tyrosine Dephosphorylation Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Early Endosome To Late Endosome Transport Cilium Assembly Positive Regulation Of Wnt Protein Secretion Positive Regulation Of Homophilic Cell Adhesion Positive Regulation Of Adherens Junction Organization Positive Regulation Of Early Endosome To Late Endosome Transport	Protein Transport Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Pathways		Interleukin-37 signaling	Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy
Drugs
Diseases
GWAS		C-reactive protein levels ( 30388399) Refractive error ( 32231278) Type 2 diabetes (adjusted for BMI) ( 29632382)	Creatine kinase levels ( 29403010) Fruit consumption ( 32066663) Pulse pressure ( 30224653)
Interacting Genes		11 interacting genes: ALG2 CEP19 CEP55 CHMP4B DDX24 LRRK2 NOTCH2NLA PSMA3 TRIM27 UBAP1 UBC	5 interacting genes: ITGA5 MAP3K1 PPIC PTPN23 UBC
Entrez ID		25930	51271
HPRD ID		05959	15597
Ensembl ID		ENSG00000076201	ENSG00000165006
Uniprot IDs		B4DST5 Q9H3S7	A0A6G6AA68 Q9NZ09
PDB IDs		3RAU 5CRU 5CRV 5LM1 5LM2 5MJY 5MJZ 5MK0 5MK1 5MK2 5MK3	1WGN 4AE4 5LM1
Enriched GO Terms of Interacting Partners?
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