NELFB and TPRX1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		NELFB	TPRX1
Description		negative elongation factor complex member B	tetrapeptide repeat homeobox 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm NELF Complex	Chromatin Nucleus
	Molecular Function	RNA Binding Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
	Biological Process	Cell Population Proliferation Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Stem Cell Differentiation Negative Regulation Of Stem Cell Differentiation	Regulation Of Transcription By RNA Polymerase II
Pathways		Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation NTRK3 as a dependence receptor
Drugs
Diseases
GWAS
Interacting Genes		17 interacting genes: BRCA1 CEBPE DENR ESR1 EXOSC2 FOS HSPA9 JUN KHDRBS3 MAPK6 MGST1 NELFE NTRK3 RAD51 TPRX1 TUBB4B WDR5	18 interacting genes: ATXN1 FANCG GOLGA2 GOLGA6L9 INCA1 KRTAP19-7 KRTAP6-2 MKRN3 NELFB OIP5 PRR20A PRR20B PRR20C PRR20D PRR20E SERTAD3 USHBP1 ZNRF4
Entrez ID		25920	284355
HPRD ID		10845	13447
Ensembl ID		ENSG00000188986	ENSG00000178928
Uniprot IDs		Q8WX92	Q8N7U7
PDB IDs		6GML
Enriched GO Terms of Interacting Partners?
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