RCHY1 and RPN2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		RCHY1	RPN2
Description		ring finger and CHY zinc finger domain containing 1	ribophorin II
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GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck Intracellular Membrane-bounded Organelle	Autophagosome Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Oligosaccharyltransferase Complex Membrane Integral Component Of Membrane Nuclear Body
	Molecular Function	P53 Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Protein Homodimerization Activity Ubiquitin Protein Ligase Activity	Dolichyl-diphosphooligosaccharide-protein Glycotransferase Activity Protein Binding Ribosome Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Error-free Translesion Synthesis	Cellular Protein Modification Process Protein N-linked Glycosylation Aging Response To Xenobiotic Stimulus Protein N-linked Glycosylation Via Asparagine
Pathways		Translesion Synthesis by POLH Antigen processing: Ubiquitination & Proteasome degradation	SRP-dependent cotranslational protein targeting to membrane Asparagine N-linked glycosylation Maturation of spike protein
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Response to tocilizumab in rheumatoid arthritis ( 22491018)	Height ( 31562340) Hippocampal atrophy ( 19668339) Initial pursuit acceleration in psychotic disorders ( 29064472) Kawasaki disease ( 33692975)
Interacting Genes		75 interacting genes: ADAMTSL4 AIG1 ANGPTL8 AOX1 AR ARF4 ATN1 BIRC3 CAMK2A CAMK2G CDK9 CDKN1B CHD8 CHEK2 COPE COX6C CREB5 CYBA DAPK1 DCUN1D5 F7 FADS6 GFI1B GORAB HOXA1 HOXA2 HOXA3 HOXB1 HOXB2 HOXB5 HOXC11 HOXC4 HOXD10 HRG KAT5 KLHL41 KRTAP9-2 LIMS2 MDM2 MEOX2 MSH3 MT2A NKD2 NLK NOTCH2NLA PGLS PLAGL2 PMM1 PRDX4 RAB11A RBM38 RILP RPLP1 RPN2 SEMA4C SERPINA1 SERPINA5 SERTAD1 SRPRB TAOK2 TMBIM1 TMEM14C TMEM184A TP53 TP63 TP73 TRIM8 UBASH3B UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 WDR74 ZNF160	12 interacting genes: ADRM1 EZH2 FBN3 LTB4R2 NDRG1 NGFR PTEN RBBP4 RCHY1 RHOA SLC22A2 SMO
Entrez ID		25898	6185
HPRD ID		07607	01609
Ensembl ID		ENSG00000163743	ENSG00000118705
Uniprot IDs		Q96PM5	P04844
PDB IDs		2JRJ 2K2C 2K2D	6S7O 6S7T
Enriched GO Terms of Interacting Partners?
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