RCHY1 and SEMA4C

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		RCHY1	SEMA4C
Description		ring finger and CHY zinc finger domain containing 1	semaphorin 4C
Image
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck Intracellular Membrane-bounded Organelle	Extracellular Space Integral Component Of Plasma Membrane Postsynaptic Density Synaptic Vesicle Membrane Postsynaptic Density Membrane
	Molecular Function	P53 Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Protein Homodimerization Activity Ubiquitin Protein Ligase Activity	Protein Binding Semaphorin Receptor Binding Chemorepellent Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Error-free Translesion Synthesis	Neural Crest Cell Migration Neural Tube Closure Axon Guidance Cell Migration In Hindbrain Cerebellum Development Positive Regulation Of Cell Migration Positive Regulation Of Stress-activated MAPK Cascade Muscle Cell Differentiation Negative Regulation Of Axon Extension Involved In Axon Guidance Negative Chemotaxis Semaphorin-plexin Signaling Pathway
Pathways		Translesion Synthesis by POLH Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Response to tocilizumab in rheumatoid arthritis ( 22491018)	Blood protein levels ( 30072576)
Interacting Genes		75 interacting genes: ADAMTSL4 AIG1 ANGPTL8 AOX1 AR ARF4 ATN1 BIRC3 CAMK2A CAMK2G CDK9 CDKN1B CHD8 CHEK2 COPE COX6C CREB5 CYBA DAPK1 DCUN1D5 F7 FADS6 GFI1B GORAB HOXA1 HOXA2 HOXA3 HOXB1 HOXB2 HOXB5 HOXC11 HOXC4 HOXD10 HRG KAT5 KLHL41 KRTAP9-2 LIMS2 MDM2 MEOX2 MSH3 MT2A NKD2 NLK NOTCH2NLA PGLS PLAGL2 PMM1 PRDX4 RAB11A RBM38 RILP RPLP1 RPN2 SEMA4C SERPINA1 SERPINA5 SERTAD1 SRPRB TAOK2 TMBIM1 TMEM14C TMEM184A TP53 TP63 TP73 TRIM8 UBASH3B UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 WDR74 ZNF160	20 interacting genes: CYSRT1 DLG1 DLG2 DLG3 DLG4 GIPC1 HSF2BP KRT16 KRT27 KRT31 KRT34 KRT40 KRTAP6-3 NBPF19 NCDN NOTCH2NLA PNMA1 RCHY1 TRIM54 USHBP1
Entrez ID		25898	54910
HPRD ID		07607	07257
Ensembl ID		ENSG00000163743	ENSG00000168758
Uniprot IDs		Q96PM5	Q9C0C4
PDB IDs		2JRJ 2K2C 2K2D	6N5Z
Enriched GO Terms of Interacting Partners?
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