ABI3BP and ABI3

Number of citations of the paper that reports this interaction (PubMedID 11501947)
8

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ABI3BP	ABI3
Description		ABI family member 3 binding protein	ABI family member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Collagen-containing Extracellular Matrix	Intracellular Anatomical Structure Cytoplasm Postsynaptic Density Membrane Lamellipodium SCAR Complex Dendritic Spine Dendritic Shaft
	Molecular Function	Extracellular Matrix Structural Constituent	Protein Binding SH3 Domain Binding Identical Protein Binding Actin Filament Binding
	Biological Process		Defense Response To Tumor Cell Negative Regulation Of Lamellipodium Assembly Peptidyl-tyrosine Phosphorylation Regulation Of Cell Migration Regulation Of Dendritic Spine Morphogenesis Regulation Of Postsynaptic Density Assembly Negative Regulation Of Ruffle Assembly Negative Regulation Of Protein Localization To Plasma Membrane Regulation Of Actin Cytoskeleton Reorganization Positive Regulation Of Cellular Senescence
Pathways
Drugs
Diseases
GWAS		Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced) ( 24236485) Alcohol dependence ( 26365420) Asthma (childhood onset) ( 23829686) Carotid plaque burden ( 28282560) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Gut microbiota relative abundance (Faecalibacterium) ( 33208821) Joint mobility (Beighton score) ( 27182965) Multiple sclerosis ( 31604244) Optic disc area ( 25631615 28073927) Optic disc size ( 31809533) Post bronchodilator FEV1 in COPD ( 26634245) Refractive error ( 32231278) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Alzheimer's disease (late onset) ( 28714976) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Asthma ( 31619474) Family history of Alzheimer's disease ( 30617256) Prostate cancer ( 23535732) Refractive error ( 32231278)
Interacting Genes		6 interacting genes: ABI3 CBX1 FZD5 GOT1 GRB2 MBNL1	77 interacting genes: ABI2 ABI3BP ACTN3 AGTR1 ARHGAP9 ARMC7 BAIAP2L2 BFSP2 BLOC1S5 CENPQ CEP170P1 CEP44 CYFIP2 DESI1 DTNB DTNBP1 EIF3H EIF3M EMILIN1 ENAH EVL FAM124B FARSA FBF1 GNG13 GOLM1 GRB2 HOMER1 HOMER2 HOMER3 IFT20 IHO1 KANK2 KIAA0408 KIFC3 KLC3 KLC4 KRT13 KRT14 KRT15 KRT24 KRT28 KRT31 KRT35 KRT36 KRT38 MAGEA12 MED29 MIS18A MRFAP1 MRFAP1L1 NCK2 NDEL1 NHSL2 NUP58 OIP5 PAK1 PAK2 PSMA1 RUFY3 RUNX1T1 SH3BP1 SMARCD1 SNAP23 SOS1 STX1A STX2 SUFU TMEM147 TRAF4 TXN2 VARS2 VASP WAS WASF1 WASF2 WASHC1
Entrez ID		25890	51225
HPRD ID		09380	05900
Ensembl ID		ENSG00000154175	ENSG00000108798
Uniprot IDs		Q7Z7G0	Q9P2A4
PDB IDs
Enriched GO Terms of Interacting Partners?
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