CHRDL2 and SLIT1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CHRDL2	SLIT1
Description		chordin like 2	slit guidance ligand 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm	Extracellular Space
	Molecular Function		Calcium Ion Binding Protein Binding Heparin Binding Roundabout Binding
	Biological Process	Ossification Cell Differentiation Cartilage Development	Nuclear Migration Axon Guidance Motor Neuron Axon Guidance Chemorepulsion Involved In Embryonic Olfactory Bulb Interneuron Precursor Migration Retinal Ganglion Cell Axon Guidance Dorsal/ventral Axon Guidance Axon Extension Involved In Axon Guidance Forebrain Morphogenesis Negative Chemotaxis Negative Regulation Of Synapse Assembly
Pathways			Netrin-1 signaling Signaling by ROBO receptors Regulation of commissural axon pathfinding by SLIT and ROBO Regulation of cortical dendrite branching Regulation of expression of SLITs and ROBOs
Drugs
Diseases
GWAS		Allergic rhinitis ( 25085501) Blood protein levels ( 29875488) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Microalbuminuria ( 26631737) Spine bone size ( 31053729)	Bipolar disorder ( 28115744) Diastolic blood pressure (alcohol consumption interaction) ( 24376456) Mean arterial pressure (alcohol consumption interaction) ( 24376456) Obesity-related traits ( 23251661)
Interacting Genes		21 interacting genes: BANP BMP2 BMP4 BMP5 BMP6 BMP7 CHRD ENKD1 FAH FAM90A1 GDF5 GPSM3 HOXA1 INHBA MAPRE3 OTX1 PIK3R3 POU4F2 SLIT1 ZNF417 ZNF587	17 interacting genes: ADAMTSL4 ATN1 CHRDL2 CYSRT1 FHL5 FXR1 GPC1 HOXA1 KRTAP1-1 KRTAP10-8 KRTAP13-2 KRTAP13-3 MEOX2 MTNR1A ROBO1 TRIM42 ZNF620
Entrez ID		25884	6585
HPRD ID		09881	04773
Ensembl ID		ENSG00000054938	ENSG00000187122
Uniprot IDs		Q6WN34	A6H8V1 O75093
PDB IDs
Enriched GO Terms of Interacting Partners?
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