SLIT1 and KRTAP1-1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SLIT1	KRTAP1-1
Description		slit guidance ligand 1	keratin associated protein 1-1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space	Cytosol Keratin Filament
	Molecular Function	Calcium Ion Binding Protein Binding Heparin Binding Roundabout Binding	Protein Binding
	Biological Process	Nuclear Migration Axon Guidance Motor Neuron Axon Guidance Chemorepulsion Involved In Embryonic Olfactory Bulb Interneuron Precursor Migration Retinal Ganglion Cell Axon Guidance Dorsal/ventral Axon Guidance Axon Extension Involved In Axon Guidance Forebrain Morphogenesis Negative Chemotaxis Negative Regulation Of Synapse Assembly	Biological_process
Pathways		Netrin-1 signaling Signaling by ROBO receptors Regulation of commissural axon pathfinding by SLIT and ROBO Regulation of cortical dendrite branching Regulation of expression of SLITs and ROBOs	Keratinization
Drugs
Diseases
GWAS		Bipolar disorder ( 28115744) Diastolic blood pressure (alcohol consumption interaction) ( 24376456) Mean arterial pressure (alcohol consumption interaction) ( 24376456) Obesity-related traits ( 23251661)
Interacting Genes		17 interacting genes: ADAMTSL4 ATN1 CHRDL2 CYSRT1 FHL5 FXR1 GPC1 HOXA1 KRTAP1-1 KRTAP10-8 KRTAP13-2 KRTAP13-3 MEOX2 MTNR1A ROBO1 TRIM42 ZNF620	189 interacting genes: ADAM12 ADAMTSL3 ADAMTSL4 AGXT AKR7A3 ALDH3B1 ALPP AQP1 ASPSCR1 ATG9A BCAM C10orf62 C11orf87 C19orf38 CAMK2B CATIP CATSPER1 CD300LG CERK CHIC2 CHRD CHRNG CLDN2 CNNM3 CRY2 CSF1 CST2 CTRC CTSZ CYHR1 CYSLTR2 CYSRT1 DHRS1 DMRT3 DOCK2 EFNA3 EMC7 FAM221A FAM71C FAM76B FAM90A1 FARS2 FEZF1 FKBP1B FOXD4L3 FRS3 FZD10 GLP1R GNE GRN GSTP1 GUCD1 HCK HEY2 HOXA1 HOXB5 HOXB9 HOXC8 HPCAL1 HSBP1 HYAL2 IFITM2 IGSF8 IL16 INS ITGB4 ITGB5 JOSD1 KLHL38 KLK8 KRT20 KRTAP10-1 KRTAP10-11 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-3 KRTAP13-2 KRTAP2-3 KRTAP2-4 KRTAP26-1 KRTAP4-12 KRTAP4-5 KRTAP5-11 KRTAP5-4 KRTAP5-6 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1E LCE1F LCE2B LCE2C LCE2D LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LNX1 LRFN4 LRRN4 MAGOHB MAPKBP1 MELTF MGAT5B MRGBP MRPL23 MT1B MXD3 MXI1 MYOM1 NECTIN2 NECTIN3 NMU NPDC1 NR1D2 NTM NUBP2 OLIG3 OR14I1 OTX1 P2RX4 P2RY6 PCSK5 PDE9A PGAP6 PHLDA1 PRKAB2 PRKAG1 PRPF31 PSMA1 PVR QPRT R3HDM2 REM2 RNF111 RPS19BP1 RPS28 RPUSD3 RTN4RL1 SCARF1 SCNM1 SDC3 SEMA3B SHFL SLC23A1 SLC43A2 SLC6A20 SLC7A11 SLIT1 SMARCE1 SMCP SMOC1 SNAI1 SNX18 SPACA9 SPRY1 STK16 TCEANC TFAP2D TGFB1 TNP2 TSFM VASN VGLL3 VSTM4 WNT11 ZBTB48 ZBTB9 ZDHHC1 ZNF124 ZNF330 ZNF408 ZNF439 ZNF440 ZNF446 ZNF491 ZNF497 ZNF524 ZNF581 ZNF587 ZNF648 ZNF669 ZNF696 ZNF786 ZNF837
Entrez ID		6585	81851
HPRD ID		04773	12304
Ensembl ID		ENSG00000187122	ENSG00000188581
Uniprot IDs		A6H8V1 O75093	Q07627
PDB IDs
Enriched GO Terms of Interacting Partners?
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