SPATA13 and GALK1

Number of citations of the paper that reports this interaction (PubMedID 27107012)
40

Data Source:
BioGRID (two hybrid)

		SPATA13	GALK1
Description		spermatogenesis associated 13	galactokinase 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Lamellipodium Filopodium Ruffle Membrane	Cytoplasm Cytosol Membrane Extracellular Exosome
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding	Galactokinase Activity Protein Binding ATP Binding Galactose Binding
	Biological Process	Cell Migration Lamellipodium Assembly Regulation Of Cell Migration Filopodium Assembly Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction	Galactose Metabolic Process Galactose Catabolic Process Galactitol Metabolic Process Carbohydrate Phosphorylation Glycolytic Process From Galactose
Pathways		CDC42 GTPase cycle RAC1 GTPase cycle	Defective GALK1 can cause Galactosemia II (GALCT2) Galactose catabolism
Drugs			Phosphoaminophosphonic Acid-Adenylate Ester
Diseases
GWAS		Airflow obstruction ( 22837378) Autoimmune thyroid disease ( 32581359) Cerebral cortical growth ( 29682794) Depression and alcohol dependence ( 22064162) Heel bone mineral density ( 30598549) Hypothyroidism ( 27182965) Mean spheric corpuscular volume ( 32888494) Medication use (thyroid preparations) ( 31015401) Orofacial clefts ( 22419666) Plateletcrit ( 32888494) Thyroid stimulating hormone levels ( 30367059 32769997) Tumor necrosis factor receptor II (red blood cell fatty acid level interaction) ( 28820441)	Alanine aminotransferase levels ( 33547301) White blood cell count ( 32888494)
Interacting Genes		3 interacting genes: CDC42 GALK1 KHDRBS1	4 interacting genes: APP PNRC2 SPATA13 SUMO2
Entrez ID		221178	2584
HPRD ID		15427	05057
Ensembl ID		ENSG00000182957	ENSG00000108479
Uniprot IDs		A0A024RDM6 B4DMC2 E9PFR9 Q96N96	P51570 V9HWE7
PDB IDs			1WUU 1YH7 6GR2 6Q3W 6Q3X 6Q8Z 6Q90 6Q91 6QJE 6ZGV 6ZGW 6ZGX 6ZGY 6ZGZ
Enriched GO Terms of Interacting Partners?
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