SNX1 and ARMC12

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SNX1	ARMC12
Description		sorting nexin 1	armadillo repeat containing 12
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Endosome Golgi Apparatus Cytosol Endosome Membrane Membrane Lamellipodium Retromer Complex Retromer, Tubulation Complex Early Endosome Membrane Vesicle Protein-containing Complex Intracellular Membrane-bounded Organelle	Nucleus
	Molecular Function	Epidermal Growth Factor Receptor Binding Insulin Receptor Binding Protein Binding Phosphatidylinositol Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding Protein Heterodimerization Activity Transferrin Receptor Binding Leptin Receptor Binding
	Biological Process	Intracellular Protein Transport Receptor Internalization Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Positive Regulation Of Protein Catabolic Process Lamellipodium Morphogenesis
Pathways
Drugs
Diseases
GWAS			Depression x herpes simplex 1 infection interaction ( 32564518) Eosinophil percentage of granulocytes ( 27863252) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		48 interacting genes: ACVR1B ACVR2B AGTRAP APP ARFIP2 ARL6IP1 ARMC12 ATXN7 CCDC148 CHRNG CMTM4 CMTM5 COQ3 EGFR F2R FAM25A FAM25C FAM25G FKBP7 FUNDC1 HCCS HGS INSR LEPR LIME1 MPC2 PDGFRB PLIN3 RABAC1 REEP5 REEP6 RHEX RTN3 RTN4 SASH1 SDCBP SDR16C5 SFT2D1 SH3GLB1 SNX2 SNX32 SNX6 SYNGR1 SYP TK1 TMEM239 UFD1 VPS35	8 interacting genes: EHHADH FA2H GAD2 RBBP4 SENP2 SNX1 SPG21 TTPA
Entrez ID		6642	221481
HPRD ID		03171	12901
Ensembl ID		ENSG00000028528	ENSG00000157343
Uniprot IDs		Q13596	Q5T9G4
PDB IDs		2I4K 4FZS
Enriched GO Terms of Interacting Partners?
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