FTL and ACO1

Number of citations of the paper that reports this interaction (PubMedID 8764614)
6

Data Source:
BioGRID (unspecified method)

		FTL	ACO1
Description		ferritin light chain	aconitase 1
Image
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Intracellular Ferritin Complex Membrane Azurophil Granule Lumen Autolysosome Extracellular Exosome	Cytoplasm Mitochondrion Endoplasmic Reticulum Golgi Apparatus Cytosol Extracellular Exosome
	Molecular Function	Iron Ion Binding Protein Binding Ferrous Iron Binding Ferric Iron Binding Identical Protein Binding	RNA Binding Aconitate Hydratase Activity Protein Binding Iron-responsive Element Binding Metal Ion Binding Citrate Dehydratase Activity 3 Iron, 4 Sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	Iron Ion Transport Cellular Iron Ion Homeostasis Intracellular Sequestering Of Iron Ion Iron Ion Homeostasis	Tricarboxylic Acid Cycle Citrate Metabolic Process Regulation Of Translation Cellular Iron Ion Homeostasis Post-embryonic Development Response To Iron(II) Ion Intestinal Absorption
Pathways		Scavenging by Class A Receptors Golgi Associated Vesicle Biogenesis Neutrophil degranulation Iron uptake and transport	Iron uptake and transport
Drugs		Iron Dextran Protoporphyrin Ferric pyrophosphate Sodium ferric gluconate complex Ferric pyrophosphate citrate
Diseases
GWAS			Asthma ( 22561531) Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Immune response to measles-mumps-rubella vaccine ( 24811271) Inflammatory skin disease ( 25574825) Lateral ventricle temporal horn volume ( 31530798) Motion sickness ( 25628336) Red blood cell count ( 32888494 27863252) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		30 interacting genes: ACO1 CLEC4G FTH1 GADD45A GLP1R GRB2 HTT IGDCC3 KNG1 KPNA3 MAP3K12 MEOX2 MPHOSPH6 MTNR1B MYOC MYOG NTAQ1 PALS2 PIK3CA PPP1CC PTN RAP2A SDCBP SLC13A1 SMAD9 SPINK7 TAF10 USHBP1 VKORC1 ZDHHC17	8 interacting genes: APP CCDC69 CDC42 CLTC FTL MYBPC1 NEB PXN
Entrez ID		2512	48
HPRD ID		00616	00013
Ensembl ID		ENSG00000087086	ENSG00000122729
Uniprot IDs		A0A384MDR3 P02792	P21399 Q9HBB2 V9HWB7
PDB IDs		2FFX 2FG4 2FG8 3KXU 4V6B 5LG8 6TR9 6TS0 6TS1 6TSA 6TSF 6TSJ 6WX6	2B3X 2B3Y
Enriched GO Terms of Interacting Partners?
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