ACO1 and CCDC69

Number of citations of the paper that reports this interaction (PubMedID 23414517)
13

Data Source:
BioGRID (two hybrid)

		ACO1	CCDC69
Description		aconitase 1	coiled-coil domain containing 69
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Endoplasmic Reticulum Golgi Apparatus Cytosol Extracellular Exosome	Nucleus Cytoplasm Midbody Spindle Midzone
	Molecular Function	RNA Binding Aconitate Hydratase Activity Protein Binding Iron-responsive Element Binding Metal Ion Binding Citrate Dehydratase Activity 3 Iron, 4 Sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding	Microtubule Binding
	Biological Process	Tricarboxylic Acid Cycle Citrate Metabolic Process Regulation Of Translation Cellular Iron Ion Homeostasis Post-embryonic Development Response To Iron(II) Ion Intestinal Absorption	Spindle Midzone Assembly
Pathways		Iron uptake and transport
Drugs
Diseases
GWAS		Asthma ( 22561531) Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Immune response to measles-mumps-rubella vaccine ( 24811271) Inflammatory skin disease ( 25574825) Lateral ventricle temporal horn volume ( 31530798) Motion sickness ( 25628336) Red blood cell count ( 32888494 27863252) Smoking status (ever vs never smokers) ( 30643258)	Bulimia nervosa ( 23568457) Chronic obstructive pulmonary disease ( 30804561) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Loneliness (linear analysis) ( 27629369) Lymphocyte counts ( 32888494) Monocyte count ( 32888494 27863252) Neutrophil count ( 32888494) Obesity-related traits ( 23251661) Red cell distribution width ( 32888494) White blood cell count ( 32888494 27863252)
Interacting Genes		8 interacting genes: APP CCDC69 CDC42 CLTC FTL MYBPC1 NEB PXN	5 interacting genes: ACO1 MAP3K1 MAP3K20 PSMA3 SMURF1
Entrez ID		48	26112
HPRD ID		00013	13152
Ensembl ID		ENSG00000122729	ENSG00000198624
Uniprot IDs		P21399 Q9HBB2 V9HWB7	A6NI79 Q7L2X4
PDB IDs		2B3X 2B3Y
Enriched GO Terms of Interacting Partners?
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