IFIT5 and IFIT3

Number of citations of the paper that reports this interaction (PubMedID 21642987)
222

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		IFIT5	IFIT3
Description		interferon induced protein with tetratricopeptide repeats 5	interferon induced protein with tetratricopeptide repeats 3
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GO Annotations	Cellular Component	Cytosol Plasma Membrane Actin Cytoskeleton Ruffle Membrane Apical Part Of Cell	Cytoplasm Mitochondrion Cytosol
	Molecular Function	TRNA Binding RNA Cap Binding Double-stranded DNA Binding RNA Binding Single-stranded RNA Binding Protein Binding Poly(U) RNA Binding	Molecular_function RNA Binding Protein Binding Identical Protein Binding
	Biological Process	Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus	Negative Regulation Of Cell Population Proliferation Response To Virus Cellular Response To Interferon-alpha Negative Regulation Of Apoptotic Process Innate Immune Response Defense Response To Virus
Pathways		Interferon alpha/beta signaling	Interferon alpha/beta signaling
Drugs
Diseases
GWAS			Hormone measurements ( 30576415)
Interacting Genes		17 interacting genes: A2M APOE CDC37 CHUK ECSIT IFIT1 IFIT3 IKBKG LONP1 MAST1 PRDX2 PSEN2 RAD23A RNF32 SARAF SRPK1 SRPK2	20 interacting genes: A2M APOE CYP2C8 DEUP1 ECSIT FANCA HAUS1 IFIT1 IFIT1B IFIT2 IFIT5 LONP1 LVRN MAST1 PSEN2 RAD23A RNF32 TMEM183A TPM1 TPM3
Entrez ID		24138	3437
HPRD ID		17130	05228
Ensembl ID		ENSG00000152778	ENSG00000119917
Uniprot IDs		Q13325	O14879 Q5T765
PDB IDs		3ZGQ 4HOQ 4HOR 4HOS 4HOT 4J0U	6C6K
Enriched GO Terms of Interacting Partners?
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