PPP1R15A and HABP4

Number of citations of the paper that reports this interaction (PubMedID 16455055)
10

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PPP1R15A	HABP4
Description		protein phosphatase 1 regulatory subunit 15A	hyaluronan binding protein 4
Image			No pdb structure
GO Annotations	Cellular Component	Protein Phosphatase Type 1 Complex Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Membrane	Extracellular Region Nucleus Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytosol Cytoplasmic Stress Granule Cajal Body Sarcoplasm Nuclear Speck Sarcomere Gemini Of Coiled Bodies
	Molecular Function	Protein Binding Protein Phosphatase 1 Binding Protein Phosphatase Regulator Activity Protein Kinase Binding Protein Phosphatase Activator Activity	RNA Binding Protein Binding SUMO Binding
	Biological Process	Apoptotic Process Cellular Response To DNA Damage Stimulus Positive Regulation Of Translational Initiation In Response To Stress Negative Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Phosphoprotein Phosphatase Activity Response To Endoplasmic Reticulum Stress Negative Regulation Of Protein Dephosphorylation Regulation Of Translational Initiation By EIF2 Alpha Dephosphorylation Regulation Of Cell Cycle Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Protein Localization To Endoplasmic Reticulum Positive Regulation Of Peptidyl-serine Dephosphorylation Negative Regulation Of PERK-mediated Unfolded Protein Response Positive Regulation Of Endoplasmic Reticulum Stress-induced EIF2 Alpha Dephosphorylation	MRNA Processing RNA Splicing PML Body Organization Positive Regulation Of RNA Splicing Negative Regulation Of DNA Binding Positive Regulation Of Translational Initiation Cellular Response To Mechanical Stimulus
Pathways		Downregulation of TGF-beta receptor signaling Response of EIF2AK1 (HRI) to heme deficiency	Platelet degranulation
Drugs			Hyaluronic acid
Diseases
GWAS		High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)	Height ( 25282103 31562340) Hip circumference adjusted for BMI ( 34021172) Household income (MTAG) ( 31844048) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		16 interacting genes: BAG1 BCAR1 CTBP2 EIF2S1 HABP4 HSPA1A KIF3A KMT2A LYN POU3F3 PPP1CA PPP1R1A RAD21 SMARCB1 TSN ZNF512B	26 interacting genes: C1QBP CHD3 CRK DAXX ENO2 FRA10AC1 HMGXB4 KAT5 OGT PIAS3 PPP1R15A PRKCA PRKCB PRKCD PRKCG PRKCQ PRKCZ PRMT1 RACK1 SRSF9 SYNCRIP TOPORS TP53 UBE2I VIM YBX1
Entrez ID		23645	22927
HPRD ID		06572	13628
Ensembl ID		ENSG00000087074	ENSG00000130956
Uniprot IDs		O75807	Q5JVS0
PDB IDs		4XPN
Enriched GO Terms of Interacting Partners?
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