Description |
Cbl proto-oncogene C |
Raf-1 proto-oncogene, serine/threonine kinase |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Alzheimer's disease (onset between ages 58 and 79) ( 30979435)
- Alzheimer's disease or family history of Alzheimer's disease ( 30617256)
- Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)
- Apolipoprotein B levels ( 32203549)
- Body mass index ( 26426971)
- Body mass index (age>50) ( 26426971)
- Body mass index x age interaction ( 26426971)
- Body mass index x sex x age interaction (4df test) ( 26426971)
- Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321)
- LDL cholesterol ( 24507774)
- Weight ( 28552196)
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- Asthma ( 32296059)
- Body shape index ( 34021172)
- Cardiac hypertrophy ( 21348951)
- Carotid intima media thickness x smoking interaction ( 32117412)
- Cholesterol, total ( 24097068 20686565)
- Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
- HDL cholesterol levels ( 32203549)
- Hip index ( 34021172)
- Total cholesterol levels ( 28334899)
- Waist circumference adjusted for body mass index ( 34021172)
- Waist-hip index ( 34021172)
- Waist-to-hip ratio adjusted for BMI ( 34021172 26426971)
- Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
- Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
- Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
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Interacting Genes |
54 interacting genes:
AKT1
BAP1
BIRC2
CCND2
CDK6
CDKN2B
CHFR
CKM
CRK
EGFR
EPHA2
ERBB2
FGFR4
FYN
GLIS2
GRB2
ITCH
LATS2
LYN
MAP2K3
MDM4
MYC
NACAD
NF2
NFIC
NSD3
OTUD6A
OXA1L
RAF1
SH3GL3
SHC1
SPRY2
SRC
STK11
TERT
TGFB1I1
TP53
TRAF4
TRIM46
TRIP6
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2H
UBE2I
UBE2K
UBE2L3
UBE2L6
UBE2R2
USP2
USP21
YES1
ZAP70
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160 interacting genes:
ABCB5
ADCY6
AGTR1
AKT1
AR
ARNT
ARRB2
BAD
BAG1
BCL2
BCL2L1
BCL6
BECN1
BIRC2
BIRC3
BRAF
CASZ1
CBLC
CCND2
CCT3
CD44
CDC25A
CDC37
CDK4
CDK6
CDKN2A
CDKN2B
CDKN2C
CFLAR
CNKSR1
COPS3
COPS7A
CPS1
DCAF8
DMPK
EFEMP1
EGFR
EPHA2
ERBB2
ERBIN
FGFR4
FYCO1
FYN
GLIS2
GNB2
GNG4
GRB10
GRM1
HERC1
HGF
HRAS
HSP90AA1
HSPA4
HSPA8
IL2RB
INSR
INTS10
ITCH
JAK1
JAK2
KEAP1
KRAS
KRT18
KRT8
KSR1
KSR2
LATS2
LCK
LOX
LRPAP1
MAP2K1
MAP2K2
MAP2K3
MAP2K5
MAP2K6
MAP3K1
MAP3K5
MAPK1
MAPK3
MAPK7
MAPK8
MAPK8IP3
MBP
MET
MRAS
MRC2
MYBPC1
MYC
NEDD4
NF1
NF2
NPLOC4
NR3C1
NRAS
NUDT14
OIP5
PACSIN3
PAK1
PAK2
PAK3
PBK
PDGFRA
PDGFRB
PDLIM2
PEBP1
PEBP4
PEX5L
PHB
PHKA2
PIN1
PKM
PPP1CC
PPP2CB
PRKAA1
PRKACA
PRKAR1A
PRKCA
PRKCD
PRKCE
PRKCZ
PRKG1
PRPF6
PURA
RANBP9
RAP1A
RAP2A
RASD2
RASSF1
RB1
RBBP8
RBL2
RFXANK
RHEB
RRAS
RRAS2
RSU1
SHOC2
SPRY2
SPRY4
SRC
STK26
STK3
STUB1
TBXA2R
TEAD2
TERT
TIMM50
TMEM70
TSC22D3
UBE2D2
VAV1
VDAC1
XIAP
YWHAB
YWHAE
YWHAG
YWHAH
YWHAQ
YWHAZ
YY1
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Entrez ID |
23624 |
5894 |
HPRD ID |
09765 |
01265 |
Ensembl ID |
ENSG00000142273
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ENSG00000132155
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Uniprot IDs |
Q9ULV8
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A0A0S2Z4L5
L7RRS6
P04049
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PDB IDs |
3OP0
3VRN
3VRO
3VRP
3VRQ
3VRR
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1C1Y
1FAQ
1FAR
1GUA
1RFA
3CU8
3IQJ
3IQU
3IQV
3KUC
3KUD
3NKX
3O8I
3OMV
4FJ3
4G0N
4G3X
4IEA
4IHL
6NTC
6NTD
6PTS
6PTW
6VJJ
6XGU
6XGV
6XHA
6XHB
6XI7
7JHP
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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