MKRN1 and YOD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MKRN1	YOD1
Description		makorin ring finger protein 1	YOD1 deubiquitinase
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytosol	Cytoplasm Cytosol
	Molecular Function	RNA Binding Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Thiol-dependent Deubiquitinase Protein Binding Ubiquitin Protein Ligase Binding Metal Ion Binding Lys63-specific Deubiquitinase Activity Deubiquitinase Activity Lys48-specific Deubiquitinase Activity
	Biological Process	Protein Polyubiquitination Protein Ubiquitination	Macroautophagy Protein Deubiquitination Ubiquitin-dependent ERAD Pathway Endoplasmic Reticulum Unfolded Protein Response Protein K29-linked Deubiquitination Protein K11-linked Deubiquitination Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination Negative Regulation Of Retrograde Protein Transport, ER To Cytosol Protein K27-linked Deubiquitination Protein K33-linked Deubiquitination
Pathways		AKT phosphorylates targets in the cytosol Regulation of PTEN stability and activity Antigen processing: Ubiquitination & Proteasome degradation	Ovarian tumor domain proteases
Drugs
Diseases
GWAS		Age at first birth ( 34211149) Age at first sexual intercourse ( 34211149) General risk tolerance (MTAG) ( 30643258) Gut microbiota relative abundance (unassigned genus belonging to family Lachnospiraceae) ( 33208821) Immature fraction of reticulocytes ( 32888494) Number of sexual partners ( 30643258)	Systolic blood pressure ( 28234671)
Interacting Genes		26 interacting genes: APC ASH2L BYSL CSNK1G1 DAXX DUSP23 EXOSC8 FADD FAM161A MAP1LC3B MTURN NAA10 OTUB2 PABPC1 RAD23A RAD23B RPS10 SDCBP SLC13A1 TSC2 UBASH3A UBE2D1 UBE2D3 UBE2D4 UBE2W YOD1	30 interacting genes: BIRC3 DAZAP2 DDIT4L FAM168A INCA1 LMO2 MKRN1 NEDD4 NGRN PLEKHB2 PSMA7 RFC2 RIPK1 RNF216 SHARPIN SNCA SPART TP53BP2 TRAF6 TRIM54 TRIM55 TRIM63 TRIM8 UBC UBE3A UBXN6 USP15 USP21 VCP ZFP57
Entrez ID		23608	55432
HPRD ID		09673	10312
Ensembl ID		ENSG00000133606	ENSG00000180667
Uniprot IDs		Q9UHC7	Q5VVQ6
PDB IDs			4BOQ 4BOS 4BOZ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
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