YOD1 and ZFP57

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		YOD1	ZFP57
Description		YOD1 deubiquitinase	ZFP57 zinc finger protein
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Nucleus
	Molecular Function	Thiol-dependent Deubiquitinase Protein Binding Ubiquitin Protein Ligase Binding Metal Ion Binding Lys63-specific Deubiquitinase Activity Deubiquitinase Activity Lys48-specific Deubiquitinase Activity	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Chromatin Binding Metal Ion Binding
	Biological Process	Macroautophagy Protein Deubiquitination Ubiquitin-dependent ERAD Pathway Endoplasmic Reticulum Unfolded Protein Response Protein K29-linked Deubiquitination Protein K11-linked Deubiquitination Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination Negative Regulation Of Retrograde Protein Transport, ER To Cytosol Protein K27-linked Deubiquitination Protein K33-linked Deubiquitination	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression By Genetic Imprinting Regulation Of Transcription By RNA Polymerase II DNA Methylation Involved In Embryo Development
Pathways		Ovarian tumor domain proteases
Drugs
Diseases
GWAS		Systolic blood pressure ( 28234671)	Albumin-globulin ratio ( 29403010) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Hip circumference adjusted for BMI ( 34021172) Offspring birth weight ( 31043758) Sepsis (hospital admission) ( 32592749) White matter integrity (mean diffusivity) ( 32358547)
Interacting Genes		30 interacting genes: BIRC3 DAZAP2 DDIT4L FAM168A INCA1 LMO2 MKRN1 NEDD4 NGRN PLEKHB2 PSMA7 RFC2 RIPK1 RNF216 SHARPIN SNCA SPART TP53BP2 TRAF6 TRIM54 TRIM55 TRIM63 TRIM8 UBC UBE3A UBXN6 USP15 USP21 VCP ZFP57	8 interacting genes: CIB3 DVL3 EMD KANK2 MKRN3 MLH1 POLR1C YOD1
Entrez ID		55432	346171
HPRD ID		10312	19560
Ensembl ID		ENSG00000180667	ENSG00000204644
Uniprot IDs		Q5VVQ6	A0A1U9X8V5 B7ZW61 Q9NU63
PDB IDs		4BOQ 4BOS 4BOZ
Enriched GO Terms of Interacting Partners?
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