KLHDC2 and ERO1A

		KLHDC2	ERO1A
Description		kelch domain containing 2	endoplasmic reticulum oxidoreductase 1 alpha
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Body Cul2-RING Ubiquitin Ligase Complex Nuclear Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Membrane Dendrite Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Ubiquitin Ligase-substrate Adaptor Activity	Protein Disulfide Isomerase Activity Protein Binding Protein-disulfide Reductase Activity Disulfide Oxidoreductase Activity Oxidoreductase Activity Thiol Oxidase Activity FAD Binding
	Biological Process	Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Via The C-end Degron Rule Pathway	Protein Folding Cellular Protein Modification Process Response To Oxidative Stress Response To Temperature Stimulus Animal Organ Senescence Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Protein Maturation By Protein Folding Extracellular Matrix Organization Endoplasmic Reticulum Unfolded Protein Response Protein Folding In Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress Cell Redox Homeostasis Brown Fat Cell Differentiation Chaperone Cofactor-dependent Protein Refolding Release Of Sequestered Calcium Ion Into Cytosol Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Cellular Response To Hypoxia
Pathways			Insulin processing Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS			Heel bone mineral density ( 30598549) Urine 6-bromotryptophan levels in chronic kidney disease ( 32572055)
Interacting Genes		9 interacting genes: ATL1 EML2 ERO1A EZH2 MIS12 SELENOK SELENOS STRN4 USP1	15 interacting genes: APPBP2 DYNLT1 EBF1 ERP44 GPX7 GPX8 KLHDC2 LHX4 LINC01554 OGT P4HB PDIA3 PDILT PELI2 RHOU
Entrez ID		23588	30001
HPRD ID		08824	13278
Ensembl ID		ENSG00000165516	ENSG00000197930
Uniprot IDs		Q9Y2U9	Q96HE7
PDB IDs		6DO3 6DO4 6DO5	3AHQ 3AHR
Enriched GO Terms of Interacting Partners?
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