CBX7 and SUV39H2

Number of citations of the paper that reports this interaction (PubMedID 21060834)
25

Data Source:
BioGRID (protein complementation assay)

		CBX7	SUV39H2
Description		chromobox 7	SUV39H2 histone lysine methyltransferase
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytosol PcG Protein Complex PRC1 Complex	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm
	Molecular Function	Protein Binding	Transcription Cis-regulatory Region Binding Protein Binding Zinc Ion Binding Histone-lysine N-methyltransferase Activity Histone Methyltransferase Activity (H3-K9 Specific) S-adenosyl-L-methionine Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Assembly Or Disassembly Chromatin Remodeling Cell Cycle Cell Differentiation Histone Lysine Methylation Histone H3-K9 Dimethylation Histone H3-K9 Trimethylation Negative Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process Cellular Response To Hypoxia
Pathways			PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Hematocrit ( 32888494) Hemoglobin ( 32888494) Immunoglobulin light chain (AL) amyloidosis ( 28025584) Lymphocyte counts ( 32888494 27863252) Menarche (age at onset) ( 25231870) Multiple myeloma ( 26007630 23955597) Multiple myeloma and monoclonal gammopathy ( 26007630) Neutrophil count ( 32888494) White blood cell count ( 32888494 27863252)	Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		8 interacting genes: B3GNT5 H3-4 PCGF1 PCGF5 PCGF6 RING1 SUV39H2 ZRANB1	41 interacting genes: AKAP9 APPL2 AR BLZF1 C8orf74 CBX7 CDCA4 CEP70 CFAP100 CGGBP1 EWSR1 FAM20C GOLGA6L9 GSTCD ID2 KCTD17 KLF3 KLHDC4 LCA5L LNX1 LRIF1 MAGEA11 MCM3AP MRFAP1 MTF2 MYL12A NME4 ODAD3 PHF19 PNMA1 POLR3F RAB3IP RASSF1 SHC1 SMAD5 SNF8 UBE2V2 WIZ ZNF212 ZNF557 ZNF57
Entrez ID		23492	79723
HPRD ID		12234	07580
Ensembl ID		ENSG00000100307	ENSG00000152455
Uniprot IDs		A0A024R1Q2 B0QYP2 O95931 Q4PNR6	Q9H5I1
PDB IDs		2K1B 2L12 2L1B 3GS2 4MN3 5EPJ 6V2R	2R3A 6P0R
Enriched GO Terms of Interacting Partners?
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