PUM2 and NANOS1

Number of citations of the paper that reports this interaction (PubMedID 12690449)
39

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		PUM2	NANOS1
Description		pumilio RNA binding family member 2	nanos C2HC-type zinc finger 1
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GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoplasmic Stress Granule Nuclear Membrane Perinuclear Region Of Cytoplasm	Cytoplasm Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding MiRNA Binding	MRNA Binding Protein Binding Zinc Ion Binding Translation Repressor Activity
	Biological Process	Regulation Of Translation Posttranscriptional Regulation Of Gene Expression Stress Granule Assembly Production Of MiRNAs Involved In Gene Silencing By MiRNA Regulation Of MRNA Stability Regulation Of Chromosome Segregation Regulation Of Gene Silencing By MiRNA Positive Regulation Of RIG-I Signaling Pathway Positive Regulation Of Gene Silencing By MiRNA	Regulation Of Cell Growth Tissue Homeostasis Posttranscriptional Regulation Of Gene Expression Epithelial Cell Migration Cell Migration Negative Regulation Of Translation Oogenesis Cerebellar Neuron Development Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Pathways		Neddylation
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) Body mass index ( 28892062) Low density lipoprotein cholesterol levels ( 32154731)	Alcoholic chronic pancreatitis ( 28754779) Keratoconus ( 33649486) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		24 interacting genes: AURKA DAZ1 DAZ3 DAZ4 DAZL MED23 MED4 MIR128-2 MIR17 MIR199A1 MIR199A2 MIR214 MIR221 MIR7-1 MIR92A2 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G NANOS1	3 interacting genes: GRIN1 GRIN2D PUM2
Entrez ID		23369	340719
HPRD ID		09527	16302
Ensembl ID		ENSG00000055917	ENSG00000188613
Uniprot IDs		B7ZL34 Q8TB72	Q8WY41
PDB IDs		3Q0Q 3Q0R 3Q0S	4CQO
Enriched GO Terms of Interacting Partners?
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