SYNM and DES

Number of citations of the paper that reports this interaction (PubMedID 11353857)
36

Data Source:
HPRD (in vitro)

		SYNM	DES
Description		synemin	desmin
Image			No pdb structure
GO Annotations	Cellular Component	Intermediate Filament Adherens Junction Sarcolemma Costamere Intermediate Filament Cytoskeleton Neurofilament Cytoskeleton	Nucleus Cytosol Intermediate Filament Fascia Adherens Intercalated Disc Z Disc Neuromuscular Junction Sarcolemma Intermediate Filament Cytoskeleton Extracellular Exosome Cardiac Myofibril
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Muscle Vinculin Binding Intermediate Filament Binding	Structural Constituent Of Cytoskeleton Protein Binding Cytoskeletal Protein Binding Identical Protein Binding
	Biological Process	Fast-twitch Skeletal Muscle Fiber Contraction Intermediate Filament Cytoskeleton Organization	Muscle Contraction Cytoskeleton Organization Regulation Of Heart Contraction Intermediate Filament Organization
Pathways			Striated Muscle Contraction
Drugs
Diseases
GWAS		Carotid plaque burden ( 28282560) Low high density lipoprotein cholesterol levels ( 26879886)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Resting heart rate ( 27798624)
Interacting Genes		7 interacting genes: DES DTNA ERBB2 ERBB3 ERBB4 PCSK6 SELENOS	62 interacting genes: ATIC AURKB B4GALT2 BAG5 BRCA1 C1orf216 CAPN1 CLIP4 CRYAB CT55 CWF19L2 DDX10 DDX6 DSP DUX1 DUX4 EHHADH ENO1 GOLGA6L9 HSPB1 ITSN1 KRT13 KRT15 KRT20 KRT33B KRT37 KRT75 LBX1 LENG1 LMO4 LONRF3 M1AP MAPKAPK2 NEB NEFL NEK6 PIAS2 PIH1D2 PKD1 PLEKHA5 POLR2G PPL PPP1R18 PRPH RNF4 ROCK1 S100A1 S100B SHBG SNAPIN SPTAN1 SYNC SYNM TCEA2 TFIP11 TRIM55 TRIM63 TRIM7 UBE2I VIM YES1 ZMYM5
Entrez ID		23336	1674
HPRD ID		07305	00514
Ensembl ID		ENSG00000182253	ENSG00000175084
Uniprot IDs		A0A075B7B1 O15061	P17661 Q53SB5
PDB IDs		6EWO
Enriched GO Terms of Interacting Partners?
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