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FMR1 and NUFIP1
Number of citations of the paper that reports this interaction (PubMedID
10556305
)
36
Data Source:
HPRD
(in vivo, in vitro, two hybrid)
FMR1
NUFIP1
Description
FMRP translational regulator 1
nuclear FMR1 interacting protein 1
Image
GO Annotations
Cellular Component
Chromosome, Centromeric Region
Nucleus
Nucleoplasm
Chromosome
Nucleolus
Cytoplasm
Cytosol
Polysome
MRNA Cap Binding Complex
Chromocenter
Cytoplasmic Stress Granule
Postsynaptic Density
Cajal Body
Membrane
Extrinsic Component Of Plasma Membrane
Axon
Dendrite
Growth Cone
Filopodium Tip
Cytoplasmic Ribonucleoprotein Granule
Presynaptic Membrane
Cell Projection
Neuron Projection
Neuronal Cell Body
Dendritic Spine
Perikaryon
Axon Terminus
Dendritic Spine Neck
Synapse
Postsynaptic Membrane
Perinuclear Region Of Cytoplasm
Neuronal Ribonucleoprotein Granule
Glial Cell Projection
Presynapse
Postsynapse
Dendritic Filopodium
Messenger Ribonucleoprotein Complex
Growth Cone Filopodium
Ribonucleoprotein Complex
Fibrillar Center
Nucleus
Nucleoplasm
Perichromatin Fibrils
Nucleolus
Transcription Elongation Factor Complex
Nuclear Matrix
Protein-containing Complex
Presynaptic Active Zone
Pre-snoRNP Complex
Molecular Function
G-quadruplex RNA Binding
Chromatin Binding
RNA Binding
MRNA Binding
MRNA 3'-UTR Binding
Protein Binding
Microtubule Binding
Poly(U) RNA Binding
Translation Repressor Activity
Translation Initiation Factor Binding
RNA Strand Annealing Activity
Poly(G) Binding
Methylated Histone Binding
SiRNA Binding
MiRNA Binding
RNA Stem-loop Binding
Identical Protein Binding
Protein Homodimerization Activity
Ribosome Binding
Transmembrane Transporter Binding
Translation Regulator Activity
Protein Heterodimerization Activity
MRNA 5'-UTR Binding
Dynein Complex Binding
Sequence-specific MRNA Binding
DNA Binding
RNA Binding
Protein Binding
SnoRNA Binding
Protein-macromolecule Adaptor Activity
Identical Protein Binding
Metal Ion Binding
ATPase Binding
Biological Process
Regulation Of Alternative MRNA Splicing, Via Spliceosome
Positive Regulation Of Protein Phosphorylation
Positive Regulation Of Receptor Internalization
MRNA Processing
Cellular Response To DNA Damage Stimulus
Glutamate Receptor Signaling Pathway
Nervous System Development
RNA Splicing
Negative Regulation Of Translation
Gene Silencing By RNA
Positive Regulation Of Histone Phosphorylation
Cellular Response To UV
Regulation Of MRNA Stability
Modulation By Host Of Viral RNA Genome Replication
Positive Regulation Of Translation
Negative Regulation Of Translational Initiation
Regulation Of Neurotransmitter Secretion
MRNA Transport
Regulation Of Filopodium Assembly
Positive Regulation Of Filopodium Assembly
Regulation Of Gene Silencing By MiRNA
Regulation Of Dendritic Spine Development
Positive Regulation Of Dendritic Spine Development
Cellular Response To Hydroxyurea
Cellular Response To Virus
Regulation Of Neuronal Action Potential
Negative Regulation Of Long-term Synaptic Depression
Positive Regulation Of Intracellular Transport Of Viral Material
Negative Regulation Of Voltage-gated Calcium Channel Activity
Positive Regulation Of Proteasomal Protein Catabolic Process
Negative Regulation Of MRNA Catabolic Process
Positive Regulation Of MRNA Binding
Negative Regulation Of Synaptic Vesicle Exocytosis
Positive Regulation Of Gene Silencing By MiRNA
Negative Regulation Of Cytoplasmic Translation
Positive Regulation Of Response To DNA Damage Stimulus
Box C/D SnoRNP Assembly
RNA Processing
Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS
Antineutrophil cytoplasmic antibody-associated vasculitis (
22808956
)
Fragile X syndrome (
30531935
)
Body mass index (
25760438
)
HDL cholesterol levels (
32203549
)
Oleic acid (18:1n-9) levels (
23362303
)
Refractive error (
32231278
)
Rosacea symptom severity (
29771307
)
Interacting Genes
48 interacting genes:
AKAP9
ALDOC
ATG5
BEX4
CALCOCO2
CAMK2B
CASK
CCAR2
CWC25
CYFIP1
CYFIP2
DCTPP1
DGKD
EFHC1
FSD2
FXR1
FXR2
GRIP2
HOMER3
INCA1
LIMS1
MAGI3
MEOX1
MVP
NCL
NECAB2
NUFIP1
NUFIP2
PICK1
POLR1C
PPP1R12C
PSME3
RANBP9
RBM14
SF3B2
SFPQ
SHARPIN
SPAG5
SRC
STAU1
SUOX
TACC2
UBE2I
WBP2NL
YBX1
ZBTB42
ZFPM2
ZMYND8
12 interacting genes:
BRCA1
CCNT1
DDX20
FMR1
GEMIN2
GEMIN4
GEMIN6
KLF6
OGT
SNU13
TAF9
ZNHIT3
Entrez ID
2332
26747
HPRD ID
02398
05073
Ensembl ID
ENSG00000102081
ENSG00000083635
Uniprot IDs
Q06787
Q9UHK0
PDB IDs
2BKD
2FMR
2LA5
2QND
4OVA
4QVZ
4QW2
5DE5
5DE8
5DEA
5UWJ
5UWO
5L85
Enriched GO Terms of Interacting Partners
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