CSTF2T and CTDSP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CSTF2T	CTDSP1
Description		cleavage stimulation factor subunit 2 tau variant	CTD small phosphatase 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Extracellular Exosome
	Molecular Function	RNA Binding MRNA Binding Protein Binding	Phosphoprotein Phosphatase Activity Protein Binding RNA Polymerase II CTD Heptapeptide Repeat Phosphatase Activity Metal Ion Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	Pre-mRNA Cleavage Required For Polyadenylation	Negative Regulation Of Protein Phosphorylation Regulation Of Transcription By RNA Polymerase II Protein Dephosphorylation Negative Regulation Of Neuron Differentiation Negative Regulation Of Neurogenesis Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs			Aspartate beryllium trifluoride Citric acid
Diseases
GWAS		Interferon alpha levels in systemic lupus erythematosus ( 25338677) Logical memory (delayed recall) in normal cognition ( 29274321) Mammographic density (non-dense area) ( 25342443)	Immature fraction of reticulocytes ( 32888494) Inflammatory bowel disease ( 23128233) Mean corpuscular hemoglobin concentration ( 32888494 27863252)
Interacting Genes		22 interacting genes: AKAP8L ATP23 CDSN COL17A1 CPSF1 CTAG1A CTAG1B CTDSP1 FAM168B FOXI1 FOXJ2 GOLGA2 HGS LASP1 PKNOX2 SMYD3 SPAG8 STH TLE5 TOX2 UBQLN1 UBQLN4	42 interacting genes: ACTN3 BAG3 CDCA3 CDKN2C CRYBA2 CSF1R CSTF2T FAAP20 FAM110A FANCL FGFR2 GPSM1 GTF2F1 ITPKB LCK LDB1 LRRC73 LTBP4 MAPKBP1 MBP MORN3 NOXA1 OSTF1 PDZD4 PLEKHM1 POLR2A PPP1R32 PTPN11 RAB3IL1 RPRD2 SCNM1 SDCBP SNAI1 STRA8 TEKT4 TRAPPC6A TYRO3 USP29 WWOX YPEL5 ZBTB16 ZSWIM8
Entrez ID		23283	58190
HPRD ID		09900	05615
Ensembl ID		ENSG00000177613	ENSG00000144579
Uniprot IDs		Q9H0L4	Q9GZU7
PDB IDs			1T9Z 1TA0 2GHQ 2GHT 3L0B 3L0C 3L0Y 3PGL 4YGY 4YH1 6DU3
Enriched GO Terms of Interacting Partners?
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