GANAB and PRKCSH

Number of citations of the paper that reports this interaction (PubMedID 22863883)
127

Data Source:
BioGRID (biochemical)
HPRD (in vitro)

		GANAB	PRKCSH
Description		glucosidase II alpha subunit	protein kinase C substrate 80K-H
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Lumen Golgi Apparatus Membrane Glucosidase II Complex Melanosome Intracellular Membrane-bounded Organelle Extracellular Exosome	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Glucosidase II Complex Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Binding Hydrolase Activity, Hydrolyzing O-glycosyl Compounds Protein Binding Carbohydrate Binding Glucan 1,3-alpha-glucosidase Activity Alpha-glucosidase Activity	Protein Kinase C Binding Calcium Ion Binding Protein Binding Transmembrane Transporter Binding Phosphoprotein Binding
	Biological Process	Carbohydrate Metabolic Process N-glycan Processing	Liver Development N-glycan Processing Intracellular Signal Transduction
Pathways		N-glycan trimming in the ER and Calnexin/Calreticulin cycle Calnexin/calreticulin cycle Maturation of spike protein Maturation of spike protein	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) N-glycan trimming in the ER and Calnexin/Calreticulin cycle Advanced glycosylation endproduct receptor signaling Post-translational protein phosphorylation Calnexin/calreticulin cycle Maturation of spike protein Maturation of spike protein
Drugs		Miglitol
Diseases
GWAS		Body shape index ( 34021172) Hip index ( 34021172) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Presence of antiphospholipid antibodies ( 27098658) Serum metabolite levels (CMS) ( 31636271)
Interacting Genes		9 interacting genes: CCNH CREB3L4 CSNK2A1 LINC01554 MAPK8 PRKCSH PRRC2A PTPRC RAP1A	12 interacting genes: ARL4D CANX ESR1 FXR1 GANAB GBA3 GET4 PTPRC RGS2 RPS6 SMARCA4 VDR
Entrez ID		23193	5589
HPRD ID		03516	03518
Ensembl ID		ENSG00000089597	ENSG00000130175
Uniprot IDs		B4DIW2 B4DSM6 B4DZ53 E9PKU7 F5H6X6 Q14697 V9HWJ0	B4DJQ5 K7ELL7 P14314
PDB IDs
Enriched GO Terms of Interacting Partners?
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