UBXN4 and GNGT1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		UBXN4	GNGT1
Description		UBX domain protein 4	G protein subunit gamma transducin 1
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GO Annotations	Cellular Component	Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol	Photoreceptor Inner Segment Heterotrimeric G-protein Complex Photoreceptor Disc Membrane
	Molecular Function	Protein Binding	GTPase Activity Protein Binding G-protein Beta-subunit Binding
	Biological Process	Response To Unfolded Protein Ubiquitin-dependent ERAD Pathway	Signal Transduction G Protein-coupled Receptor Signaling Pathway Phototransduction Protein Localization Cardiac Muscle Cell Apoptotic Process Eye Photoreceptor Cell Development Cellular Response To Hypoxia
Pathways			Activation of G protein gated Potassium channels G-protein activation Activation of the phototransduction cascade Activation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Glucagon-like Peptide-1 (GLP1) regulates insulin secretion ADP signalling through P2Y purinoceptor 12 G beta:gamma signalling through PI3Kgamma Prostacyclin signalling through prostacyclin receptor Prostacyclin signalling through prostacyclin receptor Adrenaline,noradrenaline inhibits insulin secretion Adrenaline,noradrenaline inhibits insulin secretion Ca2+ pathway Ca2+ pathway G alpha (q) signalling events G alpha (12/13) signalling events G beta:gamma signalling through PLC beta G alpha (s) signalling events ADP signalling through P2Y purinoceptor 1 ADP signalling through P2Y purinoceptor 1 G alpha (i) signalling events G alpha (z) signalling events Glucagon-type ligand receptors Thromboxane signalling through TP receptor Vasopressin regulates renal water homeostasis via Aquaporins Thrombin signalling through proteinase activated receptors (PARs) Thrombin signalling through proteinase activated receptors (PARs) Presynaptic function of Kainate receptors Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding G beta:gamma signalling through BTK G beta:gamma signalling through CDC42 Extra-nuclear estrogen signaling ADORA2B mediated anti-inflammatory cytokines production Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs
Diseases
GWAS		Body mass index ( 26426971) Chronotype ( 30696823)	Body mass index ( 28552196) Body size at age 10 ( 32376654) Heart rate response to recovery post exercise (10 sec) ( 29497042) Heart rate response to recovery post exercise (20 sec) ( 29497042) Heart rate response to recovery post exercise (30 sec) ( 29497042) Heart rate response to recovery post exercise (40 sec) ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) Mosquito bite size ( 28199695) Resting heart rate ( 29769521 27798624) Taxane-induced peripheral neuropathy in breast cancer ( 29278617)
Interacting Genes		5 interacting genes: GNGT1 MAILR TOM1L1 UBQLN1 VCP	14 interacting genes: GNAS GNB1 GNB2 GNB4 GNB5 GORASP2 IKBKG MSANTD4 NAGA PDCL PLEKHB1 RHO UBXN4 ZNF277
Entrez ID		23190	2792
HPRD ID		18254	01805
Ensembl ID		ENSG00000144224	ENSG00000127928
Uniprot IDs		Q92575	P63211
PDB IDs		2KXJ	7L0P 7L0Q 7L0R 7L0S
Enriched GO Terms of Interacting Partners?
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