GNGT1 and PDCL

Number of citations of the paper that reports this interaction (PubMedID 25675501)
17

Data Source:
BioGRID (pull down)

		GNGT1	PDCL
Description		G protein subunit gamma transducin 1	phosducin like
Image			No pdb structure
GO Annotations	Cellular Component	Photoreceptor Inner Segment Heterotrimeric G-protein Complex Photoreceptor Disc Membrane	Cytoplasm Cytosol Cilium
	Molecular Function	GTPase Activity Protein Binding G-protein Beta-subunit Binding	Protein Binding Protein-containing Complex Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Phototransduction Protein Localization Cardiac Muscle Cell Apoptotic Process Eye Photoreceptor Cell Development Cellular Response To Hypoxia	Protein Folding Signal Transduction Visual Perception Regulation Of G Protein-coupled Receptor Signaling Pathway Cell Projection Organization Positive Regulation Of Smoothened Signaling Pathway Negative Regulation Of Protein Refolding Heterotrimeric G-protein Complex Assembly
Pathways		Activation of G protein gated Potassium channels G-protein activation Activation of the phototransduction cascade Activation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Glucagon-like Peptide-1 (GLP1) regulates insulin secretion ADP signalling through P2Y purinoceptor 12 G beta:gamma signalling through PI3Kgamma Prostacyclin signalling through prostacyclin receptor Prostacyclin signalling through prostacyclin receptor Adrenaline,noradrenaline inhibits insulin secretion Adrenaline,noradrenaline inhibits insulin secretion Ca2+ pathway Ca2+ pathway G alpha (q) signalling events G alpha (12/13) signalling events G beta:gamma signalling through PLC beta G alpha (s) signalling events ADP signalling through P2Y purinoceptor 1 ADP signalling through P2Y purinoceptor 1 G alpha (i) signalling events G alpha (z) signalling events Glucagon-type ligand receptors Thromboxane signalling through TP receptor Vasopressin regulates renal water homeostasis via Aquaporins Thrombin signalling through proteinase activated receptors (PARs) Thrombin signalling through proteinase activated receptors (PARs) Presynaptic function of Kainate receptors Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding G beta:gamma signalling through BTK G beta:gamma signalling through CDC42 Extra-nuclear estrogen signaling ADORA2B mediated anti-inflammatory cytokines production Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Drugs
Diseases
GWAS		Body mass index ( 28552196) Body size at age 10 ( 32376654) Heart rate response to recovery post exercise (10 sec) ( 29497042) Heart rate response to recovery post exercise (20 sec) ( 29497042) Heart rate response to recovery post exercise (30 sec) ( 29497042) Heart rate response to recovery post exercise (40 sec) ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) Mosquito bite size ( 28199695) Resting heart rate ( 29769521 27798624) Taxane-induced peripheral neuropathy in breast cancer ( 29278617)	Obesity-related traits ( 23251661)
Interacting Genes		14 interacting genes: GNAS GNB1 GNB2 GNB4 GNB5 GORASP2 IKBKG MSANTD4 NAGA PDCL PLEKHB1 RHO UBXN4 ZNF277	11 interacting genes: CCT3 CCT5 GNB1 GNGT1 GRK2 IKBKG LRRK2 MFHAS1 MRPL11 PSMC5 TCP1
Entrez ID		2792	5082
HPRD ID		01805	05108
Ensembl ID		ENSG00000127928	ENSG00000136940
Uniprot IDs		P63211	Q13371
PDB IDs		7L0P 7L0Q 7L0R 7L0S
Enriched GO Terms of Interacting Partners?
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