ERC1 and DNAJC5

Number of citations of the paper that reports this interaction (PubMedID 29997244)
6

Data Source:
BioGRID (fluorescent resonance energy transfer)

		ERC1	DNAJC5
Description		ELKS/RAB6-interacting/CAST family member 1	DnaJ heat shock protein family (Hsp40) member C5
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Centrosome IkappaB Kinase Complex Ciliary Basal Body Presynaptic Membrane Synapse Cytoskeleton Of Presynaptic Active Zone	Mitochondrion Lysosomal Membrane Golgi Apparatus Cytosol Plasma Membrane Membrane Anchored Component Of Membrane Neuromuscular Junction Azurophil Granule Membrane Specific Granule Membrane Melanosome Chromaffin Granule Membrane Intracellular Membrane-bounded Organelle Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Anchored Component Of Synaptic Vesicle Membrane
	Molecular Function	Protein Binding PDZ Domain Binding Small GTPase Binding Leucine Zipper Domain Binding Cadherin Binding Structural Constituent Of Presynaptic Active Zone	Protein Binding ATP-dependent Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated I-kappaB Phosphorylation Neuromuscular Synaptic Transmission Multicellular Organism Development Protein Transport Retrograde Transport, Endosome To Golgi Negative Regulation Of Apoptotic Process Regulation Of Synaptic Plasticity Maintenance Of Presynaptic Active Zone Structure Positive Regulation Of NF-kappaB Transcription Factor Activity	Exocytosis Synaptic Vesicle Exocytosis Negative Regulation Of Neuron Apoptotic Process Regulated Exocytosis Chaperone-mediated Protein Folding Regulation Of Synaptic Vesicle Cycle
Pathways			Neutrophil degranulation GABA synthesis, release, reuptake and degradation Sensory processing of sound by inner hair cells of the cochlea
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder (hyperactivity-impulsivity symptoms) ( 32595297) Body mass index ( 26426971) Forehead morphology ( 29921221) Height ( 29782485) Lumbar spine bone mineral density ( 22504420) Medial temporal lobe substructure volumes ( 32768867) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Immature fraction of reticulocytes ( 32888494) Mean platelet volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Prostate cancer ( 23535732)
Interacting Genes		19 interacting genes: APP CD163 CRIP1 DNAJC5 FGF23 FPR2 GALNT8 GPRC5D IFFO1 ITSN2 MRTFB NCAPD2 PPFIA1 PRMT8 RAB6A RAB6B RIMS1 SRPK2 YWHAG	49 interacting genes: AGFG1 AP2B1 ARHGEF15 BTC CADM1 CADPS CD2 CFTR CGB5 CLCN3 ERC1 FAS FCHO1 GRM8 HBA2 KHDC4 LIN7A LIN7C NECAP1 NRXN3 PPFIA4 PRKACA PRKCG PRRC2B PSMD12 RABGEF1 RBSN SCAMP3 SCAMP5 SH3GL3 SLC17A8 SLC18A2 SLC30A3 SLC32A1 SNAP29 SNAP91 SNCA STX12 STX3 STX4 STX6 SV2A SYT12 SYT5 SYT9 VAMP1 VAMP3 VAMP4 VAMP7
Entrez ID		23085	80331
HPRD ID		06181	08539
Ensembl ID		ENSG00000082805	ENSG00000101152
Uniprot IDs		G8JLD3 Q8IUD2 X6RLX0	Q6AHX3 Q9H3Z4
PDB IDs			2N04 2N05
Enriched GO Terms of Interacting Partners?
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