LIMCH1 and LRIG3

Number of citations of the paper that reports this interaction (PubMedID 30429017)
6

Data Source:
BioGRID (two hybrid)

		LIMCH1	LRIG3
Description		LIM and calponin homology domains 1	leucine rich repeats and immunoglobulin like domains 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Stress Fiber Cytoplasm	Extracellular Space Plasma Membrane Integral Component Of Membrane Cytoplasmic Vesicle Membrane Extracellular Matrix
	Molecular Function	Actin Binding Myosin II Head/neck Binding Metal Ion Binding	Protein Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation Negative Regulation Of Cell Migration Actomyosin Structure Organization Positive Regulation Of Stress Fiber Assembly Regulation Of Focal Adhesion Assembly Cytoplasmic Actin-based Contraction Involved In Cell Motility	Otolith Morphogenesis
Pathways
Drugs
Diseases
GWAS		Deep white matter hyperintensities ( 32517579) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) Estimated glomerular filtration rate ( 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) Longevity (90 years and older) ( 25199915) Macular thickness ( 30535121) Optic disc size ( 31809533) Response to statins (LDL cholesterol change) ( 25350695)	Blood protein levels ( 30072576 29875488) Heart failure ( 20445134) Hematocrit ( 29403010) Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311)
Interacting Genes		2 interacting genes: APP LRIG3	3 interacting genes: LIMCH1 LMO7 MTDH
Entrez ID		22998	121227
HPRD ID		11125	08317
Ensembl ID		ENSG00000064042	ENSG00000139263
Uniprot IDs		B7Z2J4 B7Z656 D6RD46 E9PDJ9 G5EA03 Q9UPQ0	C9K080 Q6UXM1
PDB IDs
Enriched GO Terms of Interacting Partners?
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